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I01 BX004492

Funded outputs count: 30
Funder award ID: I01 BX004492
OpenAlex ID: G3338008254
MitoQ reduces senescence burden in doxorubicin-treated endothelial cells by reducing mitochondrial ROS and DNA damage
2025 · Hossein Abdeahad, Denisse G. Moreno, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 13
Senolytic therapy increases replicative capacity by eliminating senescent endothelial cells
2025 · Hossein Abdeahad, Denisse G. Moreno, et al. · Experimental Gerontology · 2
Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity
2025 · Daniel R. Machin, Md. Torikul Islam, et al. · Aging · 1
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Late‐Life Aerobic Exercise Attenuates DNA Damage and Telomere Dysfunction in Non‐Atheroprone but Not in Atheroprone Aortic Regions
2025 · Jisok Lim, John Kim, et al. · Aging Cell · 1
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Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice
2024 · Md Torikul Islam, Jinjin Cai, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 19
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Endothelial cell‐specific reduction in mTOR ameliorates age‐related arterial and metabolic dysfunction
2023 · Md Torikul Islam, Shelby A. Hall, et al. · Aging Cell · 22
Reduction of double-strand DNA break repair exacerbates vascular aging
2023 · Samuel I. Bloom, Jordan R. Tucker, et al. · Aging · 12
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Analysis of Somatic Mutations in Senescent Cells Using Single-Cell Whole-Genome Sequencing
2023 · Anthony J. Donato, Samuel I. Bloom, et al. · 3
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Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
2023 · Samuel I. Bloom, Yu Liu, et al. · Aging Cell · 68
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Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis
2023 · Venkateswara R. Gogulamudi, Md Torikul Islam, et al. · PLoS ONE · 6
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Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis
2023 · Venkateswara R. Gogulamudi, Jessica R. Durrant, et al. · GeroScience · 14
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Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction
2023 · Daniel R. Machin, Daniel W. Trott, et al. · GeroScience · 24
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Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age
2023 · Md Torikul Islam, Eric Tuday, et al. · Aging Cell · 313
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Aging results in DNA damage and telomere dysfunction that is greater in endothelial versus vascular smooth muscle cells and is exacerbated in atheroprone regions
2022 · Samuel I. Bloom, Jordan R. Tucker, et al. · GeroScience · 41
Mechanisms and consequences of endothelial cell senescence
2022 · Samuel I. Bloom, Md Torikul Islam, et al. · Nature Reviews Cardiology · 501
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Ablation of Endothelial mTOR is Benign in Young Mice and Reverses Age‐Related Arterial and Metabolic Impairments in Old Mice
2022 · Md Torikul Islam, Shelby A. Hall, et al. · The FASEB Journal
Sirt1 overexpression attenuates Western‐style diet‐induced aortic stiffening in mice
2022 · Venkateswara R. Gogulamudi, Daniel R. Machin, et al. · Physiological Reports · 2
T cells mediate cell non‐autonomous arterial ageing in mice
2021 · Daniel W. Trott, Daniel R. Machin, et al. · The Journal of Physiology · 22
Multicolor fluorescence biosensors reveal a burning need for diversity in the single-cell metabolic landscape
2021 · Md Torikul Islam, William L. Holland, et al. · Trends in Endocrinology and Metabolism · 2
Aging results in endothelial cell telomere uncapping that induces senescence, arterial stiffening, and reduced nitric oxide bioavailability
2021 · Samuel Bloom, Jordan Tucker, et al. · The FASEB Journal
Senolytic Drugs, Dasatinib and Quercetin, Attenuate Adipose Tissue T Lymphocyte Infiltration and Improve Metabolic Function in Old Mice
2021 · Md. Islam, Eric Tuday, et al. · The FASEB Journal · 3
Telomere uncapping as a possible mechanism for chemotherapy‐induced vascular toxicity
2021 · Hossein Abdeahad, Samuel Bloom, et al. · The FASEB Journal
Novel Method to Observe Endothelial Cell Telomere Dynamics in Regions Exposed to Lifelong Disturbed Flow in Murine Aorta
2021 · Jordan Tucker, Samuel Bloom, et al. · The FASEB Journal
T lymphocyte depletion ameliorates age-related metabolic impairments in mice
2021 · Daniel W. Trott, Md Torikul Islam, et al. · GeroScience · 27
Chronic aerobic exercise: targeting two birds with one stone
2020 · Md Torikul Islam, Shelby A Hall, et al. · The Journal of Physiology · 4
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