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Mesodermal cell fate specification in C. elegans

Description: PUBLIC HEALTH RELEVANCE: The mesodermal germ layer gives rise to a variety of functionally important cell types, including striated and non-striated muscles as well as non-muscle cells. Understanding the regulatory mechanisms underlying mesoderm diversification has widespread implications in basic biology, stem cell biology and clinical research.
Funding type: research
Funder scheme: R01
Start date: 2002-09-02
End date: 2018-06-30
Investigator: JUN LIU
Institution: CORNELL UNIVERSITY
Subfield: Aging
Funded outputs count: 31
Funder award ID: R01GM066953
OpenAlex ID: G1766521937
The Caenorhabditis elegans SMOC-1 Protein Acts Cell Nonautonomously To Promote Bone Morphogenetic Protein Signaling
2018 · Melisa S. DeGroot, Herong Shi, et al. · Genetics · 16
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Mutagenesis and Imaging Studies of BMP Signaling Mechanisms in C. elegans
2018 · Cathy Savage-Dunn, Ryan J. Gleason, et al. · Methods in molecular biology · 5
A new deletion allele of sma-4
2018 · McKillop, Alexandra N., Shi, Herong, et al. · PubMed Central · 1
The forkhead transcription factor UNC-130/FOXD integrates both BMP and Notch signaling to regulate dorsoventral patterning of the C. elegans postembryonic mesoderm
2017 · Qinfang Shen, Leila B. Toulabi, et al. · Developmental Biology · 10
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The C. elegans Spalt-like protein SEM-4 functions through the SoxC transcription factor SEM-2 to promote a proliferative blast cell fate in the postembryonic mesoderm
2017 · Qinfang Shen, Herong Shi, et al. · Developmental Biology · 9
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Two Paralogous Tetraspanins TSP-12 and TSP-14 Function with the ADAM10 Metalloprotease SUP-17 to Promote BMP Signaling in Caenorhabditis elegans
2017 · Lin Wang, Zhiyu Liu, et al. · PLoS Genetics · 15
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Promotion of Bone Morphogenetic Protein Signaling by Tetraspanins and Glycosphingolipids
2015 · Zhiyu Liu, Herong Shi, et al. · PLoS Genetics · 31
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A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
2014 · Jared J. Hale, Nirav M. Amin, et al. · Developmental Biology · 13
The neogenin/DCC homolog UNC-40 promotes BMP signaling via the RGM protein DRAG-1 in C. elegans
2013 · Chenxi Tian, Herong Shi, et al. · Development · 29
Repulsive guidance molecules (RGMs) and neogenin in bone morphogenetic protein (BMP) signaling
2013 · Chenxi Tian, Jun Liu · Molecular Reproduction and Development · 35
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Factors associated with discharge against medical advice from an alcohol and drug inpatient detoxifcation unit in Barcelona between 1993 and 2006
2012 · Gail Gilchrist, Klaus Langohr, et al. · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · 12
Ce-emerin and LEM-2: essential roles inCaenorhabditis elegansdevelopment, muscle function, and mitosis
2011 · Rachel Barkan, Adam J. Zahand, et al. · Molecular Biology of the Cell · 41
Somatic muscle specification during embryonic and post‐embryonic development in the nematode C. elegans
2011 · Michael Krause, Jun Liu · Wiley Interdisciplinary Reviews Developmental Biology · 23
The C. elegans SoxC protein SEM-2 opposes differentiation factors to promote a proliferative blast cell fate in the postembryonic mesoderm
2011 · Chenxi Tian, Herong Shi, et al. · Development · 14
The RGM protein DRAG-1 positively regulates a BMP-like signaling pathway inCaenorhabditis elegans
2010 · Chenxi Tian, Debjeet Sen, et al. · Development · 41
The FoxF/FoxC factor LET-381 directly regulates both cell fate specification and cell differentiation inC. elegansmesoderm development
2010 · Nirav M. Amin, Herong Shi, et al. · Development · 30
Two Hox cofactors, the Meis/Hth homolog UNC-62 and the Pbx/Exd homolog CEH-20, function together during C. elegans postembryonic mesodermal development
2009 · Yuan Jiang, Herong Shi, et al. · Developmental Biology · 24
Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope
2009 · Andy Golden, Jun Liu, et al. · Journal of Cell Science · 134
A conserved Six–Eya cassette acts downstream of Wnt signaling to direct non-myogenic versus myogenic fates in the C. elegans postembryonic mesoderm
2009 · Nirav M. Amin, Sung-Eun Lim, et al. · Developmental Biology · 33
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Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network
2009 · Haiyan Lei, Jun Liu, et al. · Development · 41
Mesodermal expression of the C. elegans HMX homolog mls-2 requires the PBC homolog CEH-20
2008 · Yuan Jiang, Herong Shi, et al. · Mechanisms of Development · 17
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Dorsoventral patterning of the C. elegans postembryonic mesoderm requires both LIN-12/Notch and TGFβ signaling
2007 · Marisa L. Foehr, Jun Liu · Developmental Biology · 31
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A Zn-finger/FH2-domain containing protein, FOZI-1, acts redundantly with CeMyoD to specify striated body wall muscle fates in theCaenorhabditis eleganspostembryonic mesoderm
2006 · Nirav M. Amin, Kejin Hu, et al. · Development · 32
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An unusual Zn-finger/FH2 domain protein controls a left/right asymmetric neuronal fate decision inC. elegans
2006 · Robert J. Johnston, John W. Copeland, et al. · Development · 49
An antagonistic role for theC. elegansSchnurri homolog SMA-9 in modulating TGFβ signaling during mesodermal patterning
2006 · Marisa L. Foehr, Amanda S. Lindy, et al. · Development · 51
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