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表观遗传和翻译后修饰机制对衰老海马突触蛋白的影响

Amount: ¥700,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2013-01-01
End date: 2017-12-31
Investigator: 贵海 陈
Institution: 安徽医科大学
Funded outputs count: 19
Funder award ID: 81370444
OpenAlex ID: G3366313846
Dynamic changes of media prefrontal cortex astrocytic activity in response to negative stimuli in male mice
2024 · Ai-Mei Wu, Jing-Ya Zhang, et al. · Neurobiology of Stress · 5
Changed Interleukins are Associated with Sleep and/or Cognition in Chronic Insomnia Patients：A Pilot Study
2023 · Fang Wang, Zhe-Zhe Zhang, et al. · Research Square
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Effects of gestational inflammation on age-related cognitive decline and hippocampal Gdnf-GFRα1 levels in F1 and F2 generations of CD-1 Mice
2023 · Bao-Ling Luo, Zhe-Zhe Zhang, et al. · BMC Neuroscience · 9
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A postpartum enriched environment rescues impaired cognition and oxidative markers in aged mice with gestational inflammation
2022 · Yu‐Xin Zhang, Qi‐Yao Wei, et al. · Brain and Behavior · 3
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Environmental enrichment improves declined cognition induced by prenatal inflammatory exposure in aged CD-1 mice: Role of NGPF2 and PSD-95
2022 · Ming-Zhu Ni, Yue-Ming Zhang, et al. · Frontiers in Aging Neuroscience · 10
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Prenatal exposure to inflammation increases anxiety-like behaviors in F1 and F2 generations: possible links to decreased FABP7 in hippocampus
2022 · Jing Chen, Zhe-Zhe Zhang, et al. · Frontiers in Behavioral Neuroscience · 17
Comparison of Polysomnography and Cardiopulmonary Coupling in the Diagnosis of Insomnia, Obstructive Sleep Apnoea, or Comorbidity, a Pilot Study
2022 · Chen Gui-Hai, Song Xuan, et al. · Journal of Advanced Neuroscience Research
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Maternal inflammation induces spatial learning and memory impairment in the F1 and F2 generations of mice via sex-specific epigenetic mechanisms
2022 · Zhe-Zhe Zhang, Jing Chen, et al. · Brain Research Bulletin · 18
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Long-Term Environmental Enrichment Relieves Dysfunctional Cognition and Synaptic Protein Levels Induced by Prenatal Inflammation in Older CD-1 Mice
2022 · Zhe-Zhe Zhang, Li-Ping Zeng, et al. · Neural Plasticity · 12
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A Long-Term Enriched Environment Ameliorates the Accelerated Age-Related Memory Impairment Induced by Gestational Administration of Lipopolysaccharide: Role of Plastic Mitochondrial Quality Control
2021 · Zhan-Qiang Zhuang, Zhe-Zhe Zhang, et al. · Frontiers in Cellular Neuroscience · 22
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Effects of Gestational Inflammation with Postpartum Enriched Environment on Age-Related Changes in Cognition and Hippocampal Synaptic Plasticity-Related Proteins
2020 · Shi-Yu Sun, Xue-Yan Li, et al. · Neural Plasticity · 5
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Effects of Embryonic Inflammation and Adolescent Psychosocial Environment on Cognition and Hippocampal Staufen in Middle-Aged Mice
2020 · Yong-Fang Wu, Yue-Ming Zhang, et al. · Frontiers in Aging Neuroscience · 14
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Effects of Prenatal Exposure to Inflammation Coupled With Stress Exposure During Adolescence on Cognition and Synaptic Protein Levels in Aged CD-1 Mice
2020 · Zhe-Zhe Zhang, Zhan-Qiang Zhuang, et al. · Frontiers in Aging Neuroscience · 14
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Lipopolysaccharide exposure during late embryogenesis triggers and drives Alzheimer‐like behavioral and neuropathological changes in CD‐1 mice
2020 · Fang Wang, Zhe‐Zhe Zhang, et al. · Brain and Behavior · 17
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Accelerated Deficits of Spatial Learning and Memory Resulting From Prenatal Inflammatory Insult Are Correlated With Abnormal Phosphorylation and Methylation of Histone 3 in CD-1 Mice
2019 · Zi-Xing Wu, Lei Cao, et al. · Frontiers in Aging Neuroscience · 18
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Inflammatory insult during pregnancy accelerates age-related behavioral and neurobiochemical changes in CD-1 mice
2016 · Xue-Yan Li, Fang Wang, et al. · AGE · 19
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Maternal inflammation linearly exacerbates offspring age-related changes of spatial learning and memory, and neurobiology until senectitude
2016 · Xue-Wei Li, Lei Cao, et al. · Behavioural Brain Research · 29
Chronic acarbose treatment alleviates age-related behavioral and biochemical changes in SAMP8 mice
2015 · Jing-Jing Tong, Gui-Hai Chen, et al. · Behavioural Brain Research · 39
Long-term acarbose administration alleviating the impairment of spatial learning and memory in the SAMP8 mice was associated with alleviated reduction of insulin system and acetylated H4K8
2015 · Wen-Wen Yan, Gui-Hai Chen, et al. · Brain Research · 35
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