Award

Improving the early prediction of cardiovascular diseases by developing novel data-driven machine learning and multiomics approaches

Description: Cardiovascular disease (CVD) begins decades before the clinical manifestations and silently reaches to irreversible advanced and serious stage. Therefore, primary prevention is of paramount importance in controlling the disease and related health care costs. Still, most existing risk prediction tools are developed for clinical cardiovascular outcomes that have limited value for primary prevention. The main aim of this study is to develop robust early cardiovascular risk prediction tool using multi-omics predictors identified with a novel machine learning method using longitudinal, multigenerational and multicohort datasets. This research project has potential to rationally shift the paradigm in preventive cardiology from detecting the likelihood of developing the disease to detecting the early biomarkers in otherwise asymptotic individuals and focus on people's lifestyle for improving cardiovascular health status.
Amount: €296,000
Funding type: fellowship
Funder scheme: Postdoctoral Researcher 2021
Start date: 2022-01-01
End date: 2025-08-31
Investigator:
Funded outputs count: 28
Funder award ID: 349708
OpenAlex ID: G3372620520
2026 · Daria Kostiniuk, Antti Blankenstein, et al. · Journal of Hypertension · 1
2025 · Katja Pahkala, Suvi Rovio, et al. · International Journal of Epidemiology · 13
2025 · Noora Kartiosuo, Kari Auranen, et al. · Environment International · 3
2025 · Veikka Lavonius, Liisa Keltikangas-Järvinen, et al. · Schizophrenia Research · 3
2024 · Pashupati P. Mishra, Binisha H. Mishra, et al. · American Journal of Preventive Cardiology · 5
2024 · Johanna Gehlen, Jie Li, et al. · Entropy · 6
2024 · Li, Jie, Hourican, Cillian, et al. · arXiv (Cornell University)
2024 · Angela Koloi, Vasileios S Loukas, et al. · European Heart Journal - Digital Health · 19
2024 · Coral del Val, Elisa Díaz de la Guardia-Bolívar, et al. · Molecular Psychiatry · 29
2023 · Tiit Örd, Tapio Lönnberg, et al. · The American Journal of Human Genetics · 49
2023 · Miikael Lehtimäki, Binisha H. Mishra, et al. · Scientific Reports · 3
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