19/22 Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study-Clinical Center
Description: The DPPOS cohort is broadly representative of the current population with pre-diabetes and Type 2 diabetes (T2D), which affect >110,000,000 individuals in the U.S. with the total cost of diabetes currently estimated at $327 billion, and provides 24 years of information on their course and complications. Understanding the effects of preventing or delaying T2D on human disease, the potential long-term benefits of lifestyle intervention and metformin, one of the most commonly used medications in the world, and the clinical course of pre-diabetes and T2D is critical if we are to apply prevention and treatment methods effectively and efficiently. We will perform new analyses to characterize the heterogeneous course of dysglycemia and its long- term complications and factors that define susceptibility or resistance to diabetes, its complications, common chronic conditions of aging, and explore the factors associated with participant retention, adherence to the protocol and completion of measurements.
Funding type: cooperative_agreement
Funder scheme: U01
Start date: 1994-08-20
End date: 2023-01-31
Investigator: DAVID S SCHADE
Institution: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
Funded outputs count: 89
Funder award ID: U01DK048407
OpenAlex ID: G8115736172