Microglial Regulation of Developing and Restored Cone Visual Circuits
Description: In late stages of age-related macular degeneration (AMD), light sensing cells (photoreceptors) in the eye die, leading to vision loss. To treat this with future approaches, we can potentially replace photoreceptors, but in order to work properly, these cells need to be able to communicate with other neurons in the eye that process light information and pass it to the brain. With this project, we will determine how microglia (immune cells of the eye) could help new photoreceptors establish connections with other neurons, potentially making future AMD treatments more effective.
Funder: BrightFocus Foundation
Amount: $180,900
Funding type: research
Funder scheme: Macular Degeneration Research: Standard
Start date: 2025-07-01
End date: 2027-06-30
Investigators: Ashley Farre, Ashley Farre
Institution: University of Idaho
Funded outputs count: 1
Funder award ID: M2025012F
OpenAlex ID: G3529528767