Proteolytic Mechanisms Mediating Cell State Transitions in Development and Stress Responses
Description: Project Narrative Emerging findings by us and others revealed unexpected non-lethal death functions of caspases. We want to understand how these non-canonical functions along with other proteolytic mechanisms are regulated to account for the developmental stage, tissue type, and environmental status of an organism. The findings from this study will help us to understand mechanisms of caspases in developmental and stress responsive cell state transitions that are important to ensure viability.
Funding type: research
Funder scheme: R35
Start date: 2019-09-01
End date: 2029-08-31
Investigator: BENJAMIN P. WEAVER
Institution: UT SOUTHWESTERN MEDICAL CENTER
Funded outputs count: 7
Funder award ID: R35GM133755
OpenAlex ID: G9000894742