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R37 DK046492

Funded outputs count: 19
Funder award ID: R37 DK046492
OpenAlex ID: G3565466736
Acute exogenous acyl-GIP treatment enhances lipid handling and fatty acid oxidation by involving brown fat
2025 · Sulayman A Lyons, Micah B S Lea, et al. · EMBO Reports · 8
Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication
2025 · Jason C.L. Tong, Charlotte Frazer-Morris, et al. · Cell Metabolism · 16
β Cell Gαs signaling is critical for physiological and pharmacological enhancement of insulin secretion
2025 · Megan E. Capozzi, David Bouslov, et al. · Journal of Clinical Investigation · 8
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Therapeutic Targeting of the GIP Receptor—Revisiting the Controversies
2025 · Jonathan E. Campbell, Daniel J. Drucker · Diabetes · 17
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Intra-islet α-cell Gs signaling promotes glucagon release
2024 · Liu Liu, Kimberley El, et al. · Nature Communications · 16
Evaluating glucose-dependent insulinotropic polypeptide and glucagon as key regulators of insulin secretion in the pancreatic islet
2024 · Sophie L. Lewandowski, Kimberley El, et al. · American Journal of Physiology-Endocrinology and Metabolism · 14
GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells
2024 · Ali H. Shilleh, Katrina Viloria, et al. · Peptides · 35
GIPR/GLP-1R dual agonist therapies for diabetes and weight loss—chemistry, physiology, and clinical applications
2023 · Jonathan E. Campbell, Timo D. Müller, et al. · Cell Metabolism · 146
The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
2023 · Kimberley El, Jonathan D. Douros, et al. · Nature Metabolism · 118
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Hypothalamic and brainstem glucose-dependent insulinotropic polypeptide receptor neurons employ distinct mechanisms to affect feeding
2023 · Alice Adriaenssens, Johannes Broichhagen, et al. · JCI Insight · 76
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Pancreas-derived DPP4 is not essential for glucose homeostasis under metabolic stress
2023 · Evgenia Fadzeyeva, Cassandra A.A. Locatelli, et al. · iScience · 5
Mechanisms controlling pancreatic islet cell function in insulin secretion
2021 · Jonathan E. Campbell, Christopher B. Newgard · Nature Reviews Molecular Cell Biology · 629
Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing
2018 · Jonathan M Haldeman, Amanda E Conway, et al. · Nucleic Acids Research · 35
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The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis
2017 · Samuel B. Stephens, Robert J. Edwards, et al. · Cell Reports · 68
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Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction
2017 · Jianyang Fu, Xiaoqing Dai, et al. · Diabetes · 50
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Metabolomics and Metabolic Diseases: Where Do We Stand?
2016 · Christopher B. Newgard · Cell Metabolism · 752
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Adenylosuccinate Is an Insulin Secretagogue Derived from Glucose-Induced Purine Metabolism
2015 · Jessica R. Gooding, Mette V. Jensen, et al. · Cell Reports · 102
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Branching Out for Detection of Type 2 Diabetes
2011 · Svati H. Shah, Laura P. Svetkey, et al. · Cell Metabolism · 28
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Metabolomics Applied to Diabetes Research
2009 · James R. Bain, Robert D. Stevens, et al. · Diabetes · 329
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