Award

Cellular and molecular mechanisms governing bladder aging.

Description: PROJECT NARRATIVE Conditions affecting the bladder such as urinary tract infections (UTIs) become more common with aging and can have a severe impact on health span and quality of life, especially among postmenopausal women. Our research aims to uncover how aging predisposes the bladder to UTIs by examining proteostasis and ribosomal and endoplasmic reticulum dynamics. Completion of this work will establish a new platform for new treatments, focusing on drugs that target aging-related bladder changes.
Amount: $400,000
Funding type: research
Funder scheme: R56
Start date: 2024-09-15
End date: 2025-08-31
Investigator: JASON C MILLS
Institution: BAYLOR COLLEGE OF MEDICINE
Funded outputs count: 4
Funder award ID: 1r56ag084691-01a1
OpenAlex ID: G3575129741
2026 · Sumiran Kasturi, Arnold M Salazar, et al. · The Journals of Gerontology Series A
2024 · Bisiayo E. Fashemi, Amala K. Rougeau, et al. · iScience · 4
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