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82171102

Funded outputs count: 60
Funder award ID: 82171102
OpenAlex ID: G3577432691
Mucoadhesive recombinant human catalase for dry eye disease: From protein engineering to first-in-human study
2026 · Ming Shao, Yiteng Lu, et al. · Med
A Receptor‐Mediated Endolysosomal Recycling Chimera Enables Catalytic TNF‐α Degradation for Sustained Treatment of Mucosal Inflammation
2026 · Wenxue Xie, Yuqing Wu, et al. · Advanced Materials
Overcoming the cytosine base editing barrier: Virus‐like particles with uracil‐DNA glycosylase inhibition unlocking the clinical potential
2026 · Yuqing Wu, Xingyu Zhu, et al. · Clinical and Translational Medicine
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An Ocular Surface‐Targeting Nucleic Acid Hydrogel for Efficient Dry Eye Disease Treatment
2026 · Yuhe Liu, Zimeng Zhai, et al. · Exploration · 1
Efficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition
2026 · Junjie Zhu, Lin Ding, et al. · Nature Biotechnology · 2
Synergistic nanosenolytic therapy reverses age-related dry eye disease by targeting cellular senescence and oxidative stress
2026 · Qianyi Ren, Xingyu Zhu, et al. · Bioactive Materials
Morphological alterations of corneal nerve after short-term scleral lens therapy for severe dry eye: an in vivo confocal microscopic study
2026 · Xiaohan Chen, Chuwei Lu, et al. · Contact Lens and Anterior Eye
Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ
2026 · Ju Zhang, Li Chen, et al. · Science Translational Medicine · 1
Itaconate derivative eye drops deploy anti-inflammatory effect in treating dry eye models
2026 · Zimeng Zhai, Yiteng Lu, et al. · Advances in Ophthalmology Practice and Research
Retina-targeted siRNA delivery via exosome–liposome hybrid vesicles for AMD treatment
2026 · Yangyang Huang, Xingyu Zhu, et al. · Biomaterials Science
Nanomicelles self-assembled using cyclosporine A–hyaluronic acid conjugates for dry eye disease treatment
2026 · Zhenyi Lin, Mingrui Cheng, et al. · Biomaterials Science
Sphingomyelin Synthase 2 Deletion Mitigates Oxidative Stress-Induced NF-κB Activation via Lipid Metabolic Reprogramming in Dry Eye Disease
2025 · Yiteng Lu, Xichen Wan, et al. · Investigative Ophthalmology & Visual Science · 5
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Identification of a blink frequency threshold for maintaining tear film stability in young adults with dry eye symptoms
2025 · Yawei Chai, Mingrui Cheng, et al. · Scientific Reports · 1
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Dynamic ocular surface secretome analysis in keratoconus patients under scleral lens intervention
2025 · Lang Zeng, Chuwei Lu, et al. · Eye Discovery
Human meibomian gland organoids to study epithelial homeostasis and dysfunction
2025 · Chuyue Yu, Xichen Wan, et al. · Protein & Cell · 5
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Itaconate-functionalized tetrahedral framework nucleic acids break the dry eye vicious cycle through dual antioxidant and anti-inflammatory actions
2025 · Kai Jiang, Zhenyi Lin, et al. · Journal of Nanobiotechnology · 6
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Characterizing inflammatory, nerve innervation, and immune alterations in three dry eye disease animal models
2025 · Yuqing Wu, Han Ye, et al. · Experimental Eye Research · 4
Engineered Un1Cas12f1 with boosted gene-editing activity and expanded genomic coverage
2025 · Li Chen, Xujiao Zhou, et al. · Proceedings of the National Academy of Sciences · 8
Identification of Matrix Metalloproteinase 3 as a Potential Biomarker for Dry Eye Disease
2025 · Xichen Wan, Mingrui Cheng, et al. · Translational Vision Science & Technology · 6
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Customised virus‐like particles: Opening a new chapter for clinical precision gene therapy
2025 · Xingyu Zhu, Qingye Zhang, et al. · Clinical and Translational Medicine
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Targeting α7 Nicotinic Acetylcholine Receptor for Modulating the Neuroinflammation of Dry Eye Disease Via Macrophages
2025 · Xujiao Zhou, Yuqing Wu, et al. · Investigative Ophthalmology & Visual Science · 13
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Clinical characteristics of dry eye patients with thyroid disorders: a cross-sectional study
2025 · Yiteng Lu, Xichen Wan, et al. · BMC Ophthalmology · 4
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Evaluation of large language models for providing educational information in orthokeratology care
2025 · Yangyi Huang, Runhan Shi, et al. · Contact Lens and Anterior Eye · 10
Customizable virus-like particles deliver CRISPR–Cas9 ribonucleoprotein for effective ocular neovascular and Huntington’s disease gene therapy
2025 · Sikai Ling, Xue Zhang, et al. · Nature Nanotechnology · 92
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A Serum Resistant Polymer with Exceptional Endosomal Escape and mRNA Delivery Efficacy for CRISPR Gene Therapy
2025 · Jia Lv, Qianqian Fan, et al. · Advanced Science · 17
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