(PQB5) Epigenetic Drivers of Hematopoietic Stem Cell Transformation
Description: PUBLIC HEALTH RELEVANCE: The results of our proposed study will significantly contribute to public health. Our data will provide necessary proof-of-principle information to develop improved patient stratification during diagnosis of acute myeloid leukemia (AML), by taking into account the order in which mutations were acquired during transformation. This knowledge will allow better classification of risk and better predictions of which targeted therapies will be effective.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R21
Start date: 2014-05-05
End date: 2017-04-30
Investigator: JENNIFER JEAN TROWBRIDGE
Institution: JACKSON LABORATORY
Funded outputs count: 10
Funder award ID: R21CA184851
OpenAlex ID: G4873086897