Epigenetic Dysregulation as a Driver of Skeletal Muscle Aging
Description: PROJECT NARRATIVE Age-related muscle loss and dysfunction, sarcopenia, represents a major public health problem as it results in loss of mobility, lack of physical independence, and increased morbidity and mortality. The primary aim of this study is to use cutting-edge bioinformatic and molecular techniques to elucidate the epigenetic mechanisms that contribute to muscle wasting in aging and to test the ability of epigenetic reprogramming to prevent or reverse these symptoms.
Funder: National Institute on Aging
Funding type: fellowship
Funder scheme: F32
Start date: 2020-09-01
End date: 2023-08-31
Investigator: AMBER LEVELL MUELLER
Institution: HARVARD MEDICAL SCHOOL
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 2
Funder award ID: F32AG069363
OpenAlex ID: G303605422