Mobile Device CBT for Chemotherapy-Related Cognitive Dysfunction: A Multi-Center Randomized Controlled Trial
Description: PROJECT NARRATIVE The proposed research will examine the efficacy of a videoconference-delivered cognitive-behavioral therapy (CBT), Memory and Attention Adaptation Training (MAAT) vs. an attention control condition (supportive therapy; ST), in a large, multi-site, randomized controlled trial (RCT) to improve subjective and objective cognitive functioning in breast cancer survivors with chemotherapy-related cognitive dysfunction (CRCD). Another goal of the research is to use functional MRI (fMRI) to evaluate underlying changes in brain activation patterns that are believed to be associated with positive effects of MAAT. If successful, results of this work will: (1) produce an evidence-based treatment that can be immediately disseminated to cancer centers and other healthcare settings to treat CRCD and (2) help inform further treatment development through improved understanding of mechanisms that promote CRCD recovery.
Funder: National Cancer Institute
Funding type: research
Funder scheme: R01
Start date: 2020-06-01
End date: 2026-05-31
Investigator: ROBERT J FERGUSON
Institution: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Funded outputs count: 24
Funder award ID: R01CA244673
OpenAlex ID: G1628193531