Environmental exposure, DNA methylation, and Parkinson's disease
Description: PUBLIC HEALTH RELEVANCE: This R21 proposal will generate crucial epigenetic data for studying the role of toxic environmental exposures in Parkinson's disease. If successful, we will identify epigenetic biomarkers of exposure and disease that can be employed more widely in other studies of pesticide health effects. The study promises to further our understanding of how environmental toxins impact neuronal and brain health. Therefore, it could ultimately improve prevention efforts, advance therapeutic developments, and inform public policy on pesticide regulation.
Funding type: research
Funder scheme: R21
Start date: 2014-08-06
End date: 2017-07-31
Investigator: STEVE HORVATH
Institution: UNIVERSITY OF CALIFORNIA LOS ANGELES
Funded outputs count: 19
Funder award ID: R21ES024356
OpenAlex ID: G1924329606