Get started
Award

Epigenetic Biomarkers of Common Chronic Diseases

Description: Narrative The goal of this proposed project is to identify new biomarkers of common diseases using epigenetic markers that are measured in the genome of easily accessible blood cells. Our project will investigate these potential epigenetic biomarkers in a high risk subgroup of the population that could benefit greatly from advanced knowledge and increased prevention.
Funding type: research
Funder scheme: RC1
Start date: 2009-09-30
End date: 2012-12-31
Investigator: SHARON L KARDIA
Institution: UNIVERSITY OF MICHIGAN AT ANN ARBOR
Funded outputs count: 44
Funder award ID: RC1HL100185
OpenAlex ID: G6787025397
Methylome-wide association analyses of lipids and modifying effects of behavioral factors in diverse race and ethnicity participants
2025 · Yao Hu, Jeff Haessler, et al. · Clinical Epigenetics · 1
PDF
Multi-Ancestry Transcriptome-Wide Association Studies of Cognitive Function, White Matter Hyperintensity, and Alzheimer’s Disease
2025 · Dima L. Chaar, Zheng Li, et al. · International Journal of Molecular Sciences · 5
Neighborhood environment associations with cognitive function and structural brain measures in older African Americans
2025 · Dima L. Chaar, Le Tu, et al. · BMC Medicine · 4
PDF
Association analysis between an epigenetic alcohol risk score and blood pressure
2024 · Helena Bui, Amena Keshawarz, et al. · Clinical Epigenetics · 3
PDF
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
2024 · Shen, J, Assimes, T.L., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill)
PDF
Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations
2024 · Jessica I. Lundin, Ulrike Peters, et al. · Epigenetics · 10
meQTL mapping in the GENOA study reveals genetic determinants of DNA methylation in African Americans
2023 · Lulu Shang, Wei Zhao, et al. · Nature Communications · 42
PDF
Epigenome‐wide association study of BMI in Black populations from InterGEN and GENOA
2022 · Jacquelyn Y. Taylor, Yunfeng Huang, et al. · Obesity · 11
PDF
Opioid Medication Use and Blood Dna Methylation: Epigenome-Wide Association Meta-Analysis
2022 · Mikyeong Lee, Roby Joehanes, et al. · Epigenomics · 12
SNP-by-CpG Site Interactions in ABCA7 Are Associated with Cognition in Older African Americans
2022 · Dima L. Chaar, Kim Nguyen, et al. · Genes · 5
PDF
Differentially Methylated DNA Regions and Left Ventricular Hypertrophy in African Americans: A HyperGEN Study
2022 · Alana C. Jones, Amit Patki, et al. · Genes · 5
PDF
METRO: Multi-ancestry transcriptome-wide association studies for powerful gene-trait association detection
2022 · Zheng Li, Wei Zhao, et al. · The American Journal of Human Genetics · 34
Epigenetics of single-site and multi-site atherosclerosis in African Americans from the Genetic Epidemiology Network of Arteriopathy (GENOA)
2022 · Farah Ammous, Wei Zhao, et al. · Clinical Epigenetics · 20
Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations
2021 · Jia Wen, Munan Xie, et al. · Genes · 19
PDF
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
2021 · Min-A Jhun, Michael Mendelson, et al. · Nature Communications · 44
Accelerated DNA methylation age and medication use among African Americans
2021 · Minjung Kho, Yi Zhe Wang, et al. · Aging · 27
PDF
Epigenetic age acceleration is associated with cardiometabolic risk factors and clinical cardiovascular disease risk scores in African Americans
2021 · Farah Ammous, Wei Zhao, et al. · Clinical Epigenetics · 102
PDF
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects
2021 · C. Christiansen, J. E. Castillo-Fernandez, et al. · Clinical Epigenetics · 83
PDF
COVID ‐19: immunopathology, pathophysiological mechanisms, and treatment options
2021 · Larissa E van Eijk, Mathijs Binkhorst, et al. · The Journal of Pathology · 149
PDF
Genome-Wide Association Study of Cardiac Structure and Systolic Function in African Americans: The Candidate Gene Association Resource (CARe) Study
2020 · Fox, Ervin R., Vasan, Ramachandran S., et al. · Carolina Digital Repository (University of North Carolina at Chapel Hill) · 6
PDF
Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans
2020 · Farah Ammous, Wei Zhao, et al. · Epigenetics · 19
PDF
Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study
2020 · Minjung Kho, Wei Zhao, et al. · BMC Medical Genomics · 23
PDF
Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA
2020 · Lulu Shang, Jennifer A. Smith, et al. · The American Journal of Human Genetics · 82
PDF
The Role of Dna Methylation in White Matter Hyperintensity Burden: an Integrative Approach
2020 · Yunju Yang · Digital Commons-TMC (Texas Medical Center)
PDF
Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans
2019 · Jennifer A. Smith, Jeremy Raisky, et al. · BMC Medical Genomics · 41
PDF
Year
Topic