DNA Repair, Mutations and Cellular Aging
Description: PROJECT NARRATIVE – Overall Multiple lines of evidence indicate a major role of DNA damage in the aging process. Here we propose to study how the role of DNA damage in aging humans is genetically controlled, what the mechanisms are that define the molecular and cellular end points of DNA damage in aging humans, and how the adverse effects of DNA damage can be minimized, thereby promoting healthy human longevity.
Funder: National Institute on Aging
Funding type: program
Funder scheme: P01
Start date: 1999-04-01
End date: 2025-04-30
Investigator: JAN VIJG
Institution: ALBERT EINSTEIN COLLEGE OF MEDICINE
Funded outputs count: 421
Funder award ID: P01AG017242
OpenAlex ID: G8093415072