Award

Development and Validation of Quantitative Anterior Segment OCT-based Methods to Evaluate Patients with Primary Angle Closure Disease

Description: PROJECT NARRATIVE The management of angle closure patients at risk for primary angle closure glaucoma (PACG), the most severe form of primary angle closure disease (PACD) and a leading cause of permanent vision loss worldwide, poses a significant challenge for eye care providers. Gonioscopy, a qualitative and subjective angle assessment method, is the current clinical standard for evaluating angle closure patients despite its limited ability to quantify PACD severity and predict progression to PACG. This project seeks to demonstrate the benefit of anterior segment optical coherence tomography (AS-OCT), a quantitative and objective angle assessment method, and develop anterior segment OCT-based methods for the clinical evaluation of patients with PACD.
Funding type: career_development
Funder scheme: K23
Start date: 2019-02-01
End date: 2024-01-31
Investigator: BENJAMIN Y. XU
Institution: UNIVERSITY OF SOUTHERN CALIFORNIA
Subfield: Ophthalmology
Field: Medicine
Funded outputs count: 47
Funder award ID: K23EY029763
OpenAlex ID: G361338383
2025 · Grace M. Richter, Benjamin Y. Xu, et al. · American Journal of Ophthalmology · 2
2025 · Kent Nguyen, Kristy Yoo, et al. · Clinical and Experimental Optometry
2024 · Kristy Yoo, Connor Lee, et al. · American Journal of Ophthalmology · 15
2024 · Jun Hui Lee, Kristy Yoo, et al. · American Journal of Ophthalmology · 16
2024 · Ryan Shean, Ning Yu, et al. · Bioengineering · 25
2024 · Kristy Yoo, Galo Apolo, et al. · American Journal of Ophthalmology · 3
2023 · Shaili S. Davuluru, Alison T. Jess, et al. · Translational Vision Science & Technology · 55
2023 · Austin Cho, Juan Pablo Lewinger, et al. · Translational Vision Science & Technology · 4
2023 · Austin Cho, Benjamin Y. Xu, et al. · American Journal of Ophthalmology · 9
2023 · Theodoros Filippopoulos, John Danias, et al. · Ophthalmology Glaucoma · 7
2023 · Sarah Zhou, Bruce Burkemper, et al. · Investigative Ophthalmology & Visual Science · 4
2023 · Yicheng K. Bao, Benjamin Y. Xu, et al. · JAMA Ophthalmology · 33
2022 · Galo Apolo, Naim Lazkani, et al. · Translational Vision Science & Technology · 5
2022 · Junhang Zhang, Javier Murgoitio-Esandi, et al. · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · 29
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