Tissue-dependent proregenerative mechanisms in adult vertebrates
Description: This proposal addresses how immune cells participate in regeneration of damaged organs in adult zebrafish. Unlike mammals, zebrafish have a remarkable capacity to regenerate their various body parts in adulthood, providing a model to understand how regeneration capacity might be induced in humans. The proposed study will define mechanisms of immune-mediated regeneration that could provide new cellular and molecular targets for stimulating replacement of damaged organs in the human injury setting
Amount: A$638,700
Funding type: research
Funder scheme: Project Grants - Standard Project Grant
Start date: 2017-01-01
End date: 2019-12-31
Investigator: Kazu Kikuchi
Institution: Victor Chang Cardiac Research Institute
Funded outputs count: 7
Funder award ID: 1130247
OpenAlex ID: G3754761447