Investigating the Role of Hepatic Glucagon Receptor Signaling in Healthspan and Aging
Description: Project Narrative: Elimination of glucagon receptor signaling shortens lifespan and healthspan in mice. Preliminary data presented in this proposal suggests that increasing glucagon signaling can improve metabolic and physical function in aging mice. Herein, we propose to extend these preliminary findings to investigate the potential to enhance glucagon signaling to extend healthspan and lifespan.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R56
Start date: 2024-04-01
End date: 2024-09-14
Investigator: JENNIFER HELENE STERN
Institution: UNIVERSITY OF ARIZONA
Funded outputs count: 2
Funder award ID: R56AG079924
OpenAlex ID: G563243995