Award

Translational Science of Gastrointestinal Cancer Initiation and Progression

Description: Project Narrative Two of the most prominent cancers of the GI tract in the U.S. are colorectal cancer (CRC) and esophageal adenocarcinoma(EAC): CRC is the second leading cause of cancer deaths, and EAC has been the fastest increasing cause of cancer deaths over the past four decades. There is clearly unmet need for effective cancer prevention and early detection for CRC and EAC. This award will provide support for an exceptional translational cancer research scientist, Dr. Yu, to perform studies that will advance our understanding of molecular alterations in the initiation and progression of GI cancers, and accelerate the development of biomarkers for cancer prevention and early detection.
Funding type: research
Funder scheme: R50
Start date: 2018-09-19
End date: 2028-08-31
Investigator: MING YU
Institution: FRED HUTCHINSON CANCER CENTER
Funded outputs count: 27
Funder award ID: R50CA233042
OpenAlex ID: G9000918300
2026 · Elena Baraznenok, Huai-Ching Hsieh, et al. · Laboratory Investigation · 1
2026 · Elena Baraznenok, Huai-Ching Hsieh, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
2025 · Xen Ping Hoi, Mary M. Stangis, et al. · Cancer Cell · 6
2025 · Victoria Cannon, Jocelyn H. Wright, et al. · Methods in molecular biology · 1
2025 · Pakdee Rojanasopondist, Andrew Kaz, et al. · Gastrointestinal Endoscopy Clinics of North America
2025 · Irina Kopyeva, Ross C. Bretherton, et al. · ACS Biomaterials Science & Engineering · 11
2024 · Aarti Kumar, Marianne Rara, et al. · Clinical and Translational Gastroenterology · 1
2024 · Mary M. Stangis, Zhengyi Chen, et al. · Cancer Discovery · 37
2024 · Namita Ganesh Hattangady, Kelly Carter, et al. · Aging · 11
2023 · Ming Yu, Kelly T. Carter, et al. · Cancer Epidemiology Biomarkers & Prevention · 4
2022 · Ming Yu, Helen R. Moinova, et al. · Clinical Cancer Research · 23
2022 · Julia Matas, Brendan Kohrn, et al. · Cancer Research · 46
2020 · William M. Grady, Ming Yu, et al. · Cancer Epidemiology Biomarkers & Prevention · 23
2020 · Ting Wang, Sean K. Maden, et al. · Clinical Epigenetics · 75
2019 · Ming Yu, William D. Hazelton, et al. · Cancer Research · 136
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