Proteomic aging clock and brain structure, cognitive decline and the risk of Alzheimers Disease and related dementias
Description: PROJECT NARRATIVE Development of blood-based measurement of biological aging will improve our understanding of the role of aging in Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) and subclinical structural brain changes and cognitive decline before the clinical onset of AD/ADRD. Our study will inform on novel strategies for the preclinical screening of AD/ADRD. The accurate assessment of biological aging may help facilitate the development of anti-aging therapies against AD/ADRD.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R21
Start date: 2022-09-15
End date: 2025-08-31
Investigator: ANNA PRIZMENT
Institution: UNIVERSITY OF MINNESOTA
Funded outputs count: 8
Funder award ID: R21AG079242
OpenAlex ID: G3836457737