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Klf4与组蛋白修饰酶协同调控血管平滑肌细胞特异基因表达的分子机制

Amount: ¥610,000
Funding type: grant
Funder scheme: 面上项目
Start date: 2016-01-01
End date: 2020-12-31
Investigator: 进坤 温
Institution: 河北医科大学
Funded outputs count: 16
Funder award ID: 31671182
OpenAlex ID: G3900182242
Exosomes‐transferred LINC00668 Contributes to Thrombosis by Promoting NETs Formation in Inflammatory Bowel Disease
2023 · Long Zhang, Bin Zheng, et al. · Advanced Science · 33
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Down-regulation of the Smad signaling by circZBTB46 via the Smad2-PDLIM5 axis to inhibit type I collagen expression
2023 · Jing YU, Wen-Zhao YAN, et al. · 老年心脏病学杂志：英文版 · 4
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KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
2022 · Xinhua Zhang, Bin Zheng, et al. · Communications Biology · 47
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circAMOTL1L Suppresses Renal Cell Carcinoma Growth by Modulating the miR‐92a‐2‐5p/KLLN Pathway
2021 · Ling Gao, Xian Shao, et al. · Oxidative Medicine and Cellular Longevity · 9
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Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission
2020 · Dong Ma, Bin Zheng, et al. · PLoS Biology · 79
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Salvia miltiorrhiza bunge exerts anti-oxidative effects through inhibiting KLF10 expression in vascular smooth muscle cells exposed to high glucose
2020 · Jing Zhou, Long Zhang, et al. · Journal of Ethnopharmacology · 30
Salvia miltiorrhiza-Derived Sal-miR-58 Induces Autophagy and Attenuates Inflammation in Vascular Smooth Muscle Cells
2020 · Yan Qin, Bin Zheng, et al. · Molecular Therapy — Nucleic Acids · 46
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Tanshinone ⅡA inhibits VSMC inflammation and proliferation in vivo and in vitro by downregulating miR-712-5p expression
2020 · Yan Qin, Bin Zheng, et al. · European Journal of Pharmacology · 27
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Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis
2020 · Gao-shan Yang, Bin Zheng, et al. · Theranostics · 43
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eIF5a reduction via decreased Klf5 leads to cell senescence by mitochondrial fission in VSMCs
2019 · Dong Ma, Bin Zheng, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Salvianolic acid B inhibits Ang II-induced VSMC proliferation in vitro and intimal hyperplasia in vivo by downregulating miR-146a expression
2018 · Xue-shan Zhao, Bin Zheng, et al. · Phytomedicine · 30
Regulatory crosstalk between KLF5, miR-29a and Fbw7/CDC4 cooperatively promotes atherosclerotic development
2017 · Bin Zheng, Cui-ying Zheng, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 37
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iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration
2017 · Man-li Zhang, Bin Zheng, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 37
Inhibition of KLF5–Myo9b–RhoA Pathway–Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm
2017 · Dong Ma, Bin Zheng, et al. · Circulation Research · 55
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1, 25(OH) 2 D 3 -induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation
2016 · Dong Ma, Ruo-nan Zhang, et al. · Biochemical and Biophysical Research Communications · 31
Mixture Synthesis and Spectroscopic Analysis of the Phytophthora Mating Hormone Alpha 1 and the Corresponding Bis-mtpa Esters
2010 · Reena Bajpai · D-Scholarship@Pitt (University of Pittsburgh)
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