Award

Control of Gene Expression and Life Span

Description: Project Narrative The approach and experiments described in this proposal have the potential to produce results that will shed light on the relationships and molecular mechanisms linking changes in chromatin structure to alterations in gene expression as they relate to aging and Alzheimer’s Diseases. Understanding these relationships will lead to the development of interventions that can ameliorate some of the deleterious consequences of aging and delay the onset and progression of Alzheimer’s Disease.
Funding type: research
Funder scheme: RF1
Start date: 2004-09-30
End date: 2024-06-30
Investigator: STEPHEN L HELFAND
Institution: BROWN UNIVERSITY
Funded outputs count: 46
Funder award ID: RF1AG024353
OpenAlex ID: G1192173718
2022 · Jackson R. Taylor, Jason G. Wood, et al. · Proceedings of the National Academy of Sciences · 55
2021 · Vera Gorbunova, Andrei Seluanov, et al. · Nature · 428
2018 · Jason G. Wood, Bjoern Schwer, et al. · Proceedings of the National Academy of Sciences · 83
2017 · Christian von Loeffelholz, Stefanie Lieske, et al. · Hepatology · 70
2016 · Brian C. Jones, Jason G. Wood, et al. · Nature Communications · 130
2016 · Jason G. Wood, Brian C. Jones, et al. · Proceedings of the National Academy of Sciences · 215
2014 · Vera Gorbunova, Jef D. Boeke, et al. · Science · 62
2014 · Feifei Ding, M. Pilar Gil, et al. · Journal of Insect Physiology · 16
2013 · Yiannis A. Savva, James E. C. Jepson, et al. · Nature Communications · 53
2013 · Rachel Whitaker, Shakeela Faulkner, et al. · Aging · 103
2013 · Blanka Rogina, Stephen L. Helfand · Frontiers in Genetics · 31
2013 · Jason G. Wood, Stephen L. Helfand · Frontiers in Genetics · 127
2012 · Khalil H. Chamseddin, Sabina Q. Khan, et al. · Mechanisms of Ageing and Development · 40
2011 · Gerald I. Shulman, Stephen L. Helfand · Aging · 8
2010 · Jason G. Wood, Sara Hillenmeyer, et al. · Aging Cell · 192
2010 · Mikhail V. Blagosklonny, Judy Campisi, et al. · Aging · 38
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