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Biology of Aging Training Grant

Description: A strong training program in the basic biology of aging will provide students and postdoctoral trainees with essential tools for becoming successful gerontologists in contemporary areas of aging research including metabolism, neuroscience, genetics and epigenetics.
Funding type: training
Funder scheme: T32
Start date: 1989-09-14
End date: 2016-04-30
Investigator: LAWRENCE A. DONEHOWER
Institution: BAYLOR COLLEGE OF MEDICINE
Subfield: Aging
Funded outputs count: 101
Funder award ID: T32AG000183
OpenAlex ID: G4654780651
Altered chromatin states drive cryptic transcription in aging mammalian stem cells
2021 · Brenna S. McCauley, Luyang Sun, et al. · Nature Aging · 66
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Loss of Ku’s DNA end binding activity affects telomere length via destabilizing telomere-bound Est1 rather than altering TLC1 homeostasis
2019 · Laramie D. Lemon, Danna K. Morris, et al. · Scientific Reports · 9
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Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines
2019 · Sveinung Lillehaug, Michael J. Yetman, et al. · Scientific Data · 3
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Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions
2018 · A. N. Johnston, W. Bu, et al. · Breast Cancer Research · 67
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Combination anti-Aβ treatment maximizes cognitive recovery and rebalances mTOR signaling in APP mice
2018 · Angie C.A. Chiang, Stephanie W. Fowler, et al. · The Journal of Experimental Medicine · 20
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The habenula as a novel link between the homeostatic and hedonic pathways in cancer‐associated weight loss: a pilot study
2018 · Maria Maldonado, David L. Molfese, et al. · Journal of Cachexia Sarcopenia and Muscle · 14
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Abstracts of the 10th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Rome, Italy, 8‐10 December 2017 (Part 2)
2018 · Frandsen, Ulrik, Kamper, Rikke Stefan, et al. · Journal of Cachexia Sarcopenia and Muscle · 5
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Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis
2017 · Angie C.A. Chiang, Stephanie W. Fowler, et al. · American Journal Of Pathology · 15
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Ghrelin deletion protects against age‐associated hepatic steatosis by downregulating the C/EBPα‐p300/DGAT1 pathway
2017 · Bobby Guillory, Nicole Jawanmardi, et al. · Aging Cell · 39
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Deletion of ghrelin prevents aging‐associated obesity and muscle dysfunction without affecting longevity
2017 · Bobby Guillory, Ji‐an Chen, et al. · Aging Cell · 37
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Evaluation of US Veterans Nutrition Education for Diabetes Prevention
2016 · Megan Erickson, Katie Braun, et al. · Journal of Nutrition Education and Behavior · 3
Is there an effect of ghrelin/ghrelin analogs on cancer? A systematic review
2016 · Sakine Sever, Donna L White, et al. · Endocrine Related Cancer · 44
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Impaired Recall of Positional Memory following Chemogenetic Disruption of Place Field Stability
2016 · Rong Zhao, Stacy D. Grunke, et al. · Cell Reports · 35
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Membrane prestin expression correlates with the magnitude of prestin-associated charge movement
2016 · Michelle L. Seymour, Lavanya Rajagopalan, et al. · Hearing Research · 10
Evaluation of Veterans MOVE! Program for Weight Loss
2016 · Katie Braun, Megan Erickson, et al. · Journal of Nutrition Education and Behavior · 13
Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction
2016 · Michael J. Yetman, Stephanie W. Fowler, et al. · PLoS ONE · 13
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The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome
2016 · Baokun He, Kazunari Nohara, et al. · Cell Metabolism · 509
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Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype
2016 · Kimberly R. Holloway, Vidya C. Sinha, et al. · International Journal of Biological Sciences · 11
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Restoration of Retarded Influenza Virus-specific Immunoglobulin Class Switch in Aged Mice
2016 · Zhang Y, Wang Y · Journal of Clinical & Cellular Immunology · 8
Widespread Neuronal Transduction of the Rodent CNS via Neonatal Viral Injection
2015 · Ji-Yoen Kim, Stacy D. Grunke, et al. · Methods in molecular biology · 15
Oxidative stress promotes benign prostatic hyperplasia
2015 · Paz Vital, Patricia Castro, et al. · The Prostate · 116
Olfaction Modulates Reproductive Plasticity through Neuroendocrine Signaling in Caenorhabditis elegans
2015 · Jessica N. Sowa, Ayse Sena Mutlu, et al. · Current Biology · 37
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Erratum: Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome
2015 · Jieqi Wang, Jan Eike Wegener, et al. · Nature · 3
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p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways
2015 · Meghan Breaux, Kyle Lewis, et al. · Molecular and Cellular Biology · 20
Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress
2015 · S M Hein, S Haricharan, et al. · Oncogene · 46
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