Defining the landscape and mechanisms of protein redox regulation during aging
Description: PROJECT NARRATIVE: Tissue aging is associated with a remodeling of redox signaling processes, and we recently developed a technology to map the protein targets of these signals comprehensively for the first time. We will apply this technology to systematically map the signaling landscape of these modifications, and investigate the mechanisms that link these processes to aging and lifespan regulation.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R56
Start date: 2021-04-15
End date: 2022-03-31
Investigator: EDWARD THOMAS CHOUCHANI
Institution: DANA-FARBER CANCER INST
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 11
Funder award ID: R56AG071966
OpenAlex ID: G8744584587