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Quantitative models of CD8+ T-cell memory

Funding type: research
Funder scheme: R01
Start date: 2001-07-01
End date: 2013-02-28
Institution: Emory University
Subfield: Immunology
Funded outputs count: 29
Funder award ID: R01AI049334
OpenAlex ID: G3929047546
Dependence of CD8 T Cell Response upon Antigen Load During Primary Infection: Analysis of Data from Yellow Fever Vaccination
2019 · James R. Moore, Hasan Ahmed, et al. · Bulletin of Mathematical Biology · 11
Population-expression models of immune response
2013 · Sean P Stromberg, Rustom Antia, et al. · Physical Biology · 4
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A Revised Timescale for Human Evolution Based on Ancient Mitochondrial Genomes
2013 · Qiaomei Fu, Alissa Mittnik, et al. · Current Biology · 717
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Peripheral selection rather than thymic involution explains sudden contraction in naive CD4 T-cell diversity with age
2012 · Philip L. F. Johnson, Andrew J. Yates, et al. · Proceedings of the National Academy of Sciences · 93
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On the Role of CD8 T Cells in the Control of Persistent Infections
2012 · Sean P. Stromberg, Rustom Antia · Biophysical Journal · 8
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How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?
2012 · Philip L. F. Johnson, Beth F. Kochin, et al. · Proceedings of the Royal Society B Biological Sciences · 17
Virus Replication Strategies and the Critical CTL Numbers Required for the Control of Infection
2011 · Andrew J. Yates, Minus Van Baalen, et al. · PLoS Computational Biology · 12
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Vaccination by delayed treatment of infection
2011 · Sean P. Stromberg, Rustom Antia · Vaccine · 6
Vaccination Alters the Balance between Protective Immunity, Exhaustion, Escape, and Death in Chronic Infections
2011 · Philip L. F. Johnson, Beth F. Kochin, et al. · Journal of Virology · 47
Homeostatic Turnover of Virus-Specific Memory CD8 T Cells Occurs Stochastically and Is Independent of CD4 T Cell Help
2010 · Daniel K Choo, Kaja Murali-Krishna, et al. · The Journal of Immunology · 64
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On the Control of Acute Rodent Malaria Infections by Innate Immunity
2010 · Beth F. Kochin, Andrew J. Yates, et al. · PLoS ONE · 27
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Visualizing recall immune responses with multi‐photon microscopy
2009 · Andrew Yates · Immunology · 1
Revisiting Estimates of CTL Killing Rates In Vivo
2007 · Andrew Yates, Frederik Graw, et al. · PLoS ONE · 46
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Estimating the Effectiveness of Simian Immunodeficiency Virus-Specific CD8+T Cells from the Dynamics of Viral Immune Escape
2007 · Judith N. Mandl, Roland R. Regoes, et al. · Journal of Virology · 44
Reconstruction of cell population dynamics using CFSE
2007 · Andrew Yates, Cliburn Chan, et al. · BMC Bioinformatics · 45
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Estimation of the rate of killing by cytotoxic T lymphocytes in vivo
2007 · Roland R. Regoes, Daniel L. Barber, et al. · Proceedings of the National Academy of Sciences · 76
Preclinical Assessment of HIV Vaccines and Microbicides by Repeated Low-Dose Virus Challenges
2005 · Roland R Regoes, Ira M Longini, et al. · PLoS Medicine · 70
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Quantifying cell turnover using CFSE data
2005 · Vitaly V. Ganusov, Sergei S. Pilyugin, et al. · Journal of Immunological Methods · 85
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Optimal Replication of Poliovirus within Cells
2005 · Roland R. Regoes, Shane Crotty, et al. · The American Naturalist · 27
How Does Cross-Reactive Stimulation Affect the Longevity of CD8+ T Cell Memory?
2005 · Vitaly V Ganusov, Sergei S Pilyugin, et al. · PLoS Computational Biology · 8
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Pharmacodynamic Functions: a Multiparameter Approach to the Design of Antibiotic Treatment Regimens
2004 · Roland R. Regoes, Camilla Wiuff, et al. · Antimicrobial Agents and Chemotherapy · 332
Roles of Target Cells and Virus-Specific Cellular Immunity in Primary Simian Immunodeficiency Virus Infection
2004 · Roland R. Regoes, Rustom Antia, et al. · Journal of Virology · 49
The rescaling method for quantifying the turnover of cell populations
2003 · Sergei S. Pilyugin, Vitaly V. Ganusov, et al. · Journal of Theoretical Biology · 48
The role of the cytotoxic T–lymphocyte response and virus cytopathogenicity in the virus decline during antiviral therapy
2003 · Vitaly V. Ganusov · Proceedings of the Royal Society B Biological Sciences · 5
Trade-offs and the evolution of virulence of microparasites: do details matter?
2003 · Vitaly V. Ganusov, Rustom Antia · Theoretical Population Biology · 59