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Competing Renewal P01

Description: PROJECT NARRATIVE: Aging is the biggest risk factor for multiple inflammation dependent chronic diseases. FGF21 is a hormone, that can lower inflammation and extend healthy lifespan. The proposed studies in this program project will study the mechanism of action of FGF21 that promotes health and test the prediction that increasing FGF21 levels in in mice will reduce age-related disease burden.
Funding type: program
Funder scheme: P01
Start date: 2016-09-15
End date: 2027-05-31
Investigator: VISHWA DEEP DIXIT
Institution: YALE UNIVERSITY
Funded outputs count: 159
Funder award ID: P01AG051459
OpenAlex ID: G9000896027
2026 · Seong J. An, Yoshihisa Suzuki, et al. · Proceedings of the National Academy of Sciences
2026 · Clair Crewe, Christy M. Gliniak, et al. · Nature Communications
2026 · Kyounghee Min, Philipp E. Scherer · Cell Research
2026 · Kim, Hee-Hoon, Mishra, Manish, et al. · Zenodo (CERN European Organization for Nuclear Research)
2026 · Xue-Nan Sun, Jan-Bernd Funcke, et al. · Science Advances · 9
2025 · Dae-Seok Kim, Jan-Bernd Funcke, et al. · Experimental & Molecular Medicine · 5
2025 · Ilja L. Kruglikov, Katarzyna Walendzik, et al. · Frontiers in Immunology · 2
2025 · Elsie Gonzalez-Hurtado, Claire Leveau, et al. · Nature Aging · 19
2025 · Bethany R. Cartwright, Philipp E. Scherer · Diabetes · 7
2025 · Milan Stoiljkovic, Jae Eun Song, et al. · Journal of Clinical Investigation · 6
2025 · Dae-Seok Kim, Toshiharu Onodera, et al. · Journal of Clinical Investigation · 6
2025 · Christy M. Gliniak, Ruth Gordillo, et al. · Cell Metabolism · 51
2025 · Aileen H. Lee, Lucie Orliaguet, et al. · Nature Metabolism · 45
2025 · Chenyang Guan, Seungjin Ryu, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 3
2025 · Yun-Hee Youm, Christy Gliniak, et al. · Nature Aging · 20
2025 · Shangang Zhao, Qingzhang Zhu, et al. · Cell Reports · 31
2024 · Hee-Hoon Kim, Vishwa Deep Dixit · Cell Metabolism · 4
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