Lifespan Vascular Biology on White Matter
Description: Project Narrative Age-related cognitive decline and dementia put an increasingly heavy burden on patients, families, and communities, and may be slowed or in many cases preventable if the key mechanisms can be identified. One of such mechanisms can be the life-time arterial vascular impacts on cerebral white matter, the portion of the brain connecting different brain regions. This study will track the lifespan relationships between several vascular functional mechanisms and white matter lifespan changes, to identify the key mechanisms that may aid prevention efforts against vascular contributions to cognitive impairment and Alzheimer's disease and promote normal, successful aging.
Funding type: research
Funder scheme: RF1
Start date: 2020-08-15
End date: 2024-08-14
Investigator: L ELLIOT ELLIOT HONG
Institution: UNIVERSITY OF MARYLAND BALTIMORE
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Funded outputs count: 76
Funder award ID: RF1NS114628
OpenAlex ID: G2308917648