Elucidation of the relationship between focal cirrhosis and hepatocellular carcinoma in nonalcoholic steatohepatitis
Description: In the manegement of chronic liver disease, it is essential to correctly assess the degree of hepatic fibrosis for appropriate surveillance of hepatocellular carcinoma. In this study, we compared the diagnostic performance of ultrasound elastography and MR elastography, which are currently used as noninvastive tests (NITs). We also examined the heterogeneity of fibrosis distribution in the liver (focal cirrhosis) by MR elastography. The diagnostic performance of MRE for fibrotic liver was higher than that of other ultrasound elastography, and the hepatic heterogeneity was as high as 30% in the same liver. The heterogeneity of liver hardness was associated with discordance with pathological biopsy.
Amount: ¥4,290,000
Funding type: research
Funder scheme: Grant-in-Aid for Scientific Research (C)
Start date: 2018-04-01
End date: 2021-03-31
Investigator: Masato YONEDA
Institution: Yokohama City University
Funded outputs count: 26
Funder award ID: 18K07637
OpenAlex ID: G4267345571