Get started
Award

Rm11916b78d5711a

Funded outputs count: 7
Funder award ID: RM11916B78D5711A
OpenAlex ID: G4269596766
BACH1/HO-1 axis dysregulation links Down syndrome to Alzheimer-like neurodegeneration
2026 · Fabio Di Domenico, Eugenio Barone, et al. · Neurochemistry International
PDF
Loss of Proteostasis and Early-Onset Neurodegeneration in Down Syndrome: From Mechanisms to Interventions
2026 · Antonella Tramutola, Chiara Lanzillotta, et al. · Antioxidants · 2
PDF
Systemic administration of the OGT inhibitor OSMI-1 normalizes hippocampal O-GlcNAcylation and improves recognition memory, redox balance, and brain mitochondrial homeostasis in a Rett syndrome mouse model
2025 · Chiara Sette, Chiara Urbinati, et al. · Free Radical Biology and Medicine · 4
Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome
2025 · Fabio Di Domenico, Viviana Greco, et al. · Molecular Neurobiology · 3
PDF
Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markers
2025 · Chiara Lanzillotta, Francesca Prestia, et al. · Redox Biology · 10
Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2
2025 · Brigitta Buttari, Antonella Tramutola, et al. · Biomolecules · 44
PDF
Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease
2023 · Marzia Perluigi, Fabio Di Domenico, et al. · Physiological Reviews · 289
Year
Topic