Award

U01 DK106993

Funder: Eunice Kennedy Shriver National Institute of Child Health and Human Development

Funded outputs count: 16

Funder award ID: U01 DK106993

OpenAlex ID: G4289150930

β-Cell Dysfunction Identifies Individuals With Single Autoantibody Positivity at Increased Risk of Type 1 Diabetes Progression

2026 · Emily K. Sims, Lu You, et al. · Diabetes Care

Quantification of Proinsulin in Human Plasma by Proteolysis-Aided Peptide Immunoaffinity-Liquid Chromatography-Tandem Mass Spectrometry

2026 · Sara K Shijo, Elisha Goonatilleke, et al. · Clinical Chemistry

Islet Autoantibody Patterns Vary by Race and Ethnicity and Area Deprivation Index for Individuals at Risk for Type 1 Diabetes

2026 · Ananta Addala, Susanne Cabrera, et al. · Diabetes Care

Predicting the Timing of the Metabolic Inflection Point in Type 1 Diabetes Progression Using Machine Learning and Survival Analysis Models

2026 · Eslam Montaser, Jay M. Sosenko, et al. · Diabetes · 1

Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort

2025 · Camille Préfontaine, Jasmine Pipella, et al. · Scientific Reports · 6

Neutrophil-enriched gene signature correlates with teplizumab therapy resistance in different stages of type 1 diabetes

2025 · Gabriele Sassi, Pierre Lemaitre, et al. · Journal of Clinical Investigation · 4

Contrasting Adult and Pediatric Populations in a Cohort of At-Risk Relatives in The T1D TrialNet Pathway to Prevention Study

2025 · Erin L. Templeman, Lauric A. Ferrat, et al. · Diabetes Care · 24

Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes

2025 · Andrea K Steck, Hemang M Parikh, et al. · The Journal of Clinical Endocrinology & Metabolism · 5

Prevention of diabetic ketoacidosis in relatives screened for islet autoantibodies and followed up in the TrialNet Pathway to Prevention study at a single institution in Italy

2025 · Sabina Martinenghi, Aurora Merolla, et al. · Diabetologia · 7

Activated polyreactive B cells are clonally expanded in autoantibody positive and patients with recent-onset type 1 diabetes

2025 · Catherine A. Nicholas, Fatima A. Tensun, et al. · Cell Reports · 11

IA-2A positivity increases risk of progression within and across established stages of type 1 diabetes

2025 · Emily K. Sims, David Cuthbertson, et al. · Diabetologia · 26

Metabolic Phenotype of Stage 1 and Stage 2 Type 1 Diabetes Using Modeling of β Cell Function

2025 · Alfonso Galderisi, Jacopo Bonet, et al. · The Journal of Clinical Endocrinology & Metabolism · 9

Teplizumab induces persistent changes in the antigen-specific repertoire in individuals at risk for type 1 diabetes

2024 · Ana Lledó-Delgado, Paula Preston-Hurlburt, et al. · Journal of Clinical Investigation · 56

Identification of type 1 diabetes risk phenotypes using an outcome-guided clustering analysis

2024 · Lu You, Lauric A. Ferrat, et al. · Diabetologia · 13

Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests

2022 · Kendra Vehik, David Boulware, et al. · Diabetes Care · 31

Circulating platelet-neutrophil aggregates characterize the development of type 1 diabetes in humans and NOD mice

2022 · Sarah K. Popp, Federica Vecchio, et al. · JCI Insight · 49