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R01DK078187

Funded outputs count: 53
Funder award ID: R01DK078187
OpenAlex ID: G43225235
The inhibitor of glycerol 3-phosphate acyltransferase FSG67 blunts liver regeneration after acetaminophen overdose by altering GSK3β and Wnt/β-catenin signaling
2019 · Melissa M. Clemens, Stefanie Kennon-McGill, et al. · Food and Chemical Toxicology · 29
Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response
2019 · Andrew J. Lutkewitte, Kyle S. McCommis, et al. · Journal of Lipid Research · 16
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Loss of lipin 1‐mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice
2018 · George G. Schweitzer, Sara L. Collier, et al. · The FASEB Journal · 40
Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21
2018 · Konrad T. Sawicki, Hsiang-Chun Chang, et al. · JCI Insight · 33
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Metabolic importance of adipose tissue monoacylglycerol acyltransferase 1 in mice and humans
2018 · Kim H.H. Liss, Andrew J. Lutkewitte, et al. · Journal of Lipid Research · 38
The impact of diet‐induced hepatic steatosis in a murine model of hepatic ischemia/reperfusion injury
2018 · Kim H. H. Liss, Kyle S. McCommis, et al. · Liver Transplantation · 37
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Antitumor effect of sorafenib and mammalian target of rapamycin inhibitor in liver transplantation recipients with hepatocellular carcinoma recurrence
2018 · Dong‐Hwan Jung, Eunyoung Tak, et al. · Liver Transplantation · 29
Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration
2018 · Andrew J. Lutkewitte, George G. Schweitzer, et al. · Food and Chemical Toxicology · 33
Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein–Induced Proinflammatory Signaling and Atherosclerosis
2017 · Aimee E. Vozenilek, Aaron R. Navratil, et al. · Arteriosclerosis Thrombosis and Vascular Biology · 39
ChREBP refines the hepatic response to fructose to protect the liver from injury
2017 · Angela M. Hall, Brian N. Finck · Journal of Clinical Investigation · 10
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Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis
2016 · Kyle S. McCommis, Wesley T. Hodges, et al. · Hepatology · 138
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PPARs and nonalcoholic fatty liver disease
2016 · Kim H.H. Liss, Brian N. Finck · Biochimie · 275
Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice
2016 · Jiayou Wang, Chunki Kim, et al. · Scientific Reports · 23
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Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis
2016 · Brian J. DeBosch, Monique R. Heitmeier, et al. · Science Signaling · 279
Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling
2015 · Kyle S. McCommis, Zhouji Chen, et al. · Cell Metabolism · 213
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Mitochondrial pyruvate transport: a historical perspective and future research directions
2015 · Kyle S. McCommis, Brian N. Finck · Biochemical Journal · 269
Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice
2015 · George G. Schweitzer, Zhouji Chen, et al. · Journal of Lipid Research · 28
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Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?
2015 · Brian N. Finck, Angela M. Hall · BioMed Research International · 47
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Rhabdomyolysis-Associated Mutations in Human LPIN1 Lead to Loss of Phosphatidic Acid Phosphohydrolase Activity
2015 · George G. Schweitzer, Sara L. Collier, et al. · JIMD Reports · 36
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Head Over Hepatocytes for FGF21
2014 · Matthew J. Potthoff, Brian N. Finck · Diabetes · 13
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Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
2014 · Nisreen Soufi, Angela M. Hall, et al. · Journal of Biological Chemistry · 51
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Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion
2014 · Patrick A. Vigueira, Kyle S. McCommis, et al. · Cell Reports · 102
Lipin 2 Binds Phosphatidic Acid by the Electrostatic Hydrogen Bond Switch Mechanism Independent of Phosphorylation
2014 · James M. Eaton, Sankeerth Takkellapati, et al. · Journal of Biological Chemistry · 35
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The Functional Characterization of Long Noncoding RNASPRY4-IT1in Human Melanoma Cells
2014 · Joseph Mazar, Wei Zhao, et al. · Oncotarget · 163
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Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
2014 · Angela M. Hall, Nisreen Soufi, et al. · Diabetes · 70
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