Pathogenic Mechanisms of Pancreatitis
Description: PUBLIC HEALTH RELEVANCE: Pancreatitis is an inflammatory disease of the pancreas that causes intense pain and, in severe cases, death. Although some predisposing factors (such as gallstones and alcohol) are known, the exact mechanisms leading to pancreatitis are not well understood. Pain-sensing nerves release transmitters that may actually cause inflammation and preliminary data indicate that these nerves play a role in pancreatitis. This proposal will characterize the neural mechanisms that contribute to pancreatitis and may lead to improved treatments of the disease.
Funding type: research
Funder scheme: R01
Start date: 2004-02-21
End date: 2019-02-28
Investigator: RODGER A. LIDDLE
Institution: DUKE UNIVERSITY
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Funded outputs count: 35
Funder award ID: R01DK064213
OpenAlex ID: G640718809