Award

81372138

Funder: National Natural Science Foundation of China

Funded outputs count: 16

Funder award ID: 81372138

OpenAlex ID: G4342856745

2-Phenylnaphthalene derivatives as RRM2 inhibitors with dual anti-tumor and anti-HBV activity in hepatocellular carcinoma

2026 · Zhiyuan Lou, Heping Zhu, et al. · Genes & Diseases

Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model

2022 · Jingwen Dong, Tingting Zhong, et al. · Cancers · 7

Super-enhancers and novel therapeutic targets in colorectal cancer

2022 · Qian Liu, Lijuan Guo, et al. · Cell Death and Disease · 31

A MYBL2 complex for RRM2 transactivation and the synthetic effect of MYBL2 knockdown with WEE1 inhibition against colorectal cancer

2021 · Qian Liu, Lijuan Guo, et al. · Cell Death and Disease · 46

Age‐related changes in metabolites in young donor livers and old recipient sera after liver transplantation from young to old rats

2021 · Qunhua Han, Hui Li, et al. · Aging Cell · 39

Osalmid, a Novel Identified RRM2 Inhibitor, Enhances Radiosensitivity of Esophageal Cancer

2020 · Qiuying Tang, Lingyun Wu, et al. · International Journal of Radiation Oncology*Biology*Physics · 33

Integrative Analysis Reveals Across-Cancer Expression Patterns and Clinical Relevance of Ribonucleotide Reductase in Human Cancers

2019 · Yongfeng Ding, Tingting Zhong, et al. · Frontiers in Oncology · 20

The inflammatory cytokine IL-6 induces FRA1 deacetylation promoting colorectal cancer stem-like properties

2019 · Tingyang Wang, Ping Song, et al. · Oncogene · 80

Protein of Vascular Endothelial Growth Inhibitor 174 Inhibits Epithelial–Mesenchymal Transition in Renal Cell Carcinoma In Vivo

2017 · QIANG ZHAO, XIAOHU DENG, et al. · Anticancer Research · 2

Identification of Novel Proteins Interacting with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma

2017 · QIANG ZHAO, DUOER KUN, et al. · Anticancer Research · 10

Physical interaction between human ribonucleotide reductase large subunit and thioredoxin increases colorectal cancer malignancy

2017 · Meng Lou, Qian Liu, et al. · Journal of Biological Chemistry · 23

Glutamate 52-β at the α/β subunit interface of Escherichia coli class Ia ribonucleotide reductase is essential for conformational gating of radical transfer

2017 · Qinghui Lin, Mackenzie J. Parker, et al. · Journal of Biological Chemistry · 37

Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase

2017 · Kanchana Ravichandran, Ellen C. Minnihan, et al. · Biochemistry · 21

ATR–CHK1–E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG

2016 · Chaoju Gong, Hong Liu, et al. · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 26

Inhibition of hepatitis B virus replication by targeting ribonucleotide reductase M2 protein

2016 · Xia Liu, Zhijian Xu, et al. · Biochemical Pharmacology · 50

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transition

2015 · Hong Liu, Guoping Ren, et al. · Carcinogenesis · 150