Clinical epidemiological study for minute myocardial damage as a marker of cardiovascular risk in patients with diabetes mellitus
Description: We aimed to examine the utility of serum high-sensitivity troponin T (hs-cTnT) as a risk marker of cardiovascular disease in patients with type 2 diabetes, using the stored serum sample and diverse clinical information that were registered in large-scale biobank.A total of 2120 patients with T2DM (mean age 61±9 years、62% men) were followed for an average of 7.7 years (maximum 11 years). When patients were divided into elevated and non-elevated hs-cTnT groups according to the value of hs-cTnT>=0.014 ng/ml and <0.014 ng/ml, respectively), elevated hs-cTnT group showed an increased risk of all-cause and cardiovascular mortality. In conclusion, an elevated hs-cTnT may predict poor prognosis in patients with T2DM.
Amount: ¥4,160,000
Funding type: research
Funder scheme: Grant-in-Aid for Scientific Research (C)
Start date: 2018-04-01
End date: 2021-03-31
Investigator: Toshiaki Otsuka
Institution: Nippon Medical School
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Funded outputs count: 0
Funder award ID: 18K10113
OpenAlex ID: G4369318792