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SASKit - Seneszenz-assoziiertes System-Diagnosekit für Krebs und Schlaganfall -- Bioinformatik, Tiermodell und Klinik

Amount: €2,265,000
Funding type: grant
Funder scheme: Systemmedizin
Start date: 2019-10-01
End date: 2024-03-31
Institution: Universitätsmedizin Rostock
Funded outputs count: 16
Funder award ID: 01ZX1903A
OpenAlex ID: G4381481915
Reduced Cerebral Infarct Volume in Young UCP2−/− Mice and Preserved Synaptic Transmission by Genipin
2026 · Gesine Reichart, Henrieke Koch, et al. · Cells
In-silico evaluation of aging-related interventions using omics data and predictive modeling
2025 · Georg Fuellen, Daniel Palmer, et al. · Ageing Research Reviews · 2
Multicohort study testing the generalisability of the SASKit-ML stroke and PDAC prognostic model pipeline to other chronic diseases
2024 · Daniel Palmer, Larissa Henze, et al. · BMJ Open · 1
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Effects of triggers of senescence and senolysis in murine pancreatic cancer cells
2024 · Denis Revskij, Aline Woitas, et al. · Hepatobiliary & pancreatic diseases international · 9
Selective but not pan-CDK inhibition abrogates 5-FU-driven tissue factor upregulation in colon cancer
2024 · Annika Kayser, Annabell Wolff, et al. · Scientific Reports
High-Dose Polyphenol-Rich Nutrition Improves Lipid and Inflammation Profiles and Can Trigger Apoptotic Signaling in Healthy Older Adults (the ErdBEHR Study)
2024 · Henrik Rudolf, Michael Walter, et al. · 2
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Healthy Aging in Times of Extreme Temperatures: Biomedical Approaches
2023 · Axel Kowald, Daniel Palmer, et al. · Aging and Disease · 4
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Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice
2022 · Denis Revskij, Jakob Runst, et al. · Hepatobiliary & pancreatic diseases international · 4
A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C : Phenotyping working group of the ILAE / AES joint translational task force
2022 · Melissa Barker‐Haliski, Julika Pitsch, et al. · Epilepsia Open · 4
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Uncoupling protein 2 deficiency of non-cancerous tissues inhibits the progression of pancreatic cancer in mice
2022 · Denis Revskij, J. Runst, et al. · Pancreatology
Protein Biomarkers in Blood Reflect the Interrelationships Between Stroke Outcome, Inflammation, Coagulation, Adhesion, Senescence and Cancer
2022 · Georg Fuellen, Uwe Walter, et al. · Cellular and Molecular Neurobiology · 10
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Transfer learning of clinical outcomes from preclinical molecular data, principles and perspectives
2022 · Axel Kowald, Israel Barrantes, et al. · Briefings in Bioinformatics · 17
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Transfer Learning of Clinical Outcomes with Molecular Data, Principles and Perspectives
2021 · Axel Kowald, Israel Barrantes, et al. · Preprints.org
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Ranking Biomarkers of Aging by Citation Profiling and Effort Scoring
2021 · Alexander Hartmann, Christiane Hartmann, et al. · Frontiers in Genetics · 80
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Towards biomarkers for outcomes after pancreatic ductal adenocarcinoma and ischaemic stroke, with focus on (co)-morbidity and ageing/cellular senescence (SASKit): protocol for a prospective cohort study
2020 · Larissa Henze, Uwe Walter, et al. · BMJ Open · 6
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The preventive strategy for pandemics in the elderly is to collect in advance samples & data to counteract chronic inflammation (inflammaging)
2020 · Georg Fuellen, Oliver Liesenfeld, et al. · Ageing Research Reviews · 27
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