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Optimising heart transplant trajectories in Fontan failure: clinical characterisation, risk stratification, and therapeutic intervention.

Description: Adults who had Fontan surgery for complex heart conditions often face serious complications as their unique circulation begins to fail. This study will assess heart function at rest and during exercise using imaging, blood tests and invasive pressure measurements, and trials treatments like milrinone and SGLT2 inhibitors to improve symptoms and stability while awaiting heart transplant. The goal is to better predict risk, guide transplant suitability, and improve outcomes for this population.

Funder: National Health and Medical Research Council

Amount: A$163,400

Funding type: fellowship

Funder scheme: Postgraduate Scholarships - Postgraduate Scholarships

Start date: 2026-01-01

End date: 2028-12-31

Investigator: Jeremy Russo

Institution: Monash University

Topic: Transplantation: Methods and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

Funded outputs count: 0

Funder award ID: 2050281

OpenAlex ID: G4443597802