Coding and Noncoding RNA Contributions to 22q11.2 Deletion Syndrome
Description: Project Narrative 22q11.2 deletion syndrome is the most common chromosomal deletion problem reported in humans, leading to multiple clinical problems that affect the immune, heart, and nervous systems. Our recent work is revealing important roles for coding and noncoding RNAs in affecting the severity of the disease. We will use patient studies and mouse models of 22q11.2 deletion syndrome to determine the impact of these RNA species in the formation and function of the thymus.
Funding type: research
Funder scheme: R01
Start date: 2015-07-01
End date: 2026-06-30
Investigator: NICOLAI STANISLAS CYRILLE VAN OERS
Institution: UT SOUTHWESTERN MEDICAL CENTER
Subfield: Molecular Biology
Domain: Life Sciences
Funded outputs count: 19
Funder award ID: R01AI114523
OpenAlex ID: G4425580381