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Mouse Metabolic Phenotyping Center

Funding type: cooperative_agreement
Funder scheme: U24
Start date: 2011-09-25
End date: 2016-08-09
Investigator: HENRI BRUNENGRABER
Institution: CASE WESTERN RESERVE UNIVERSITY
Funded outputs count: 56
Funder award ID: U24DK076174
OpenAlex ID: G2622459052
A big-data approach to understanding metabolic rate and response to obesity in laboratory mice
2020 · June K Corrigan, Deepti Ramachandran, et al. · eLife · 79
Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency
2019 · Vikram Jakkamsetti, Isaac Marin-Valencia, et al. · Science Translational Medicine · 76
Absence of leptin signaling allows fat accretion in cystic fibrosis mice
2018 · Ilya R. Bederman, Gavriella Pora, et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 12
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Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet
2018 · Jennifer M. Rutkowsky, Linda L. Lee, et al. · PLoS ONE · 60
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Macrophages with a deletion of the phosphoenolpyruvate carboxykinase 1 (Pck1) gene have a more proinflammatory phenotype
2018 · Chih-Wei Ko, Daniel Counihan, et al. · Journal of Biological Chemistry · 45
Genetic dissection in a mouse model reveals interactions between carotenoids and lipid metabolism
2016 · Grzegorz Palczewski, M.AiranthiK. Widjaja-Adhi, et al. · Journal of Lipid Research · 40
Receptor interacting protein 3 protects mice from high‐fat diet‐induced liver injury
2016 · Sanjoy Roychowdhury, Rebecca L. McCullough, et al. · Hepatology · 153
The role of α1-adrenergic receptors in regulating metabolism: increased glucose tolerance, leptin secretion and lipid oxidation
2016 · Ting Shi, Robert S. Papay, et al. · Journal of Receptors and Signal Transduction · 25
Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise
2016 · Paula Mera, Kathrin Laue, et al. · Cell Metabolism · 428
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Gastric bypass surgery is protective from high‐fat diet‐induced non‐alcoholic fatty liver disease and hepatic endoplasmic reticulum stress
2015 · J. D. Mosinski, M. R. Pagadala, et al. · Acta Physiologica · 33
[11C]acetate PET Imaging is not Always Associated with Increased Lipogenesis in Hepatocellular Carcinoma in Mice
2015 · Lei Li, Li Che, et al. · Molecular Imaging and Biology · 10
Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice
2015 · Jose Cordoba-Chacon, Neena Majumdar, et al. · Diabetes · 103
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Multiple Mass Isotopomer Tracing of Acetyl-CoA Metabolism in Langendorff-perfused Rat Hearts
2015 · Qingling Li, Shuang Deng, et al. · Journal of Biological Chemistry · 26
Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy
2015 · David A. DeSantis, Chih-Wei Ko, et al. · Mediators of Inflammation · 12
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Residues required for phosphorylation of translation initiation factor eIF2α under diverse stress conditions are divergent between yeast and human
2014 · Mithu Majumder, Daniel Mitchell, et al. · The International Journal of Biochemistry & Cell Biology · 5
Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism
2014 · David W. Frederick, James G. Davis, et al. · Journal of Biological Chemistry · 88
Decreased carbon shunting from glucose toward oxidative metabolism in diet‐induced ketotic rat brain
2014 · Yifan Zhang, Shenghui Zhang, et al. · Journal of Neurochemistry · 47
Niclosamide ethanolamine–induced mild mitochondrial uncoupling improves diabetic symptoms in mice
2014 · Hanlin Tao, Yong Zhang, et al. · Nature Medicine · 286
Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation
2014 · Emilio P. Mottillo, Priya Balasubramanian, et al. · Journal of Lipid Research · 281
Synergistic Simvastatin and Metformin Combination Chemotherapy for Osseous Metastatic Castration-Resistant Prostate Cancer
2014 · Melissa A. Babcook, Sanjeev Shukla, et al. · Molecular Cancer Therapeutics · 68
PTPRT Regulates High-Fat Diet-Induced Obesity and Insulin Resistance
2014 · Xiujing Feng, Anthony Scott, et al. · PLoS ONE · 31
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Maternal Nutrition Induces Pervasive Gene Expression Changes but No Detectable DNA Methylation Differences in the Liver of Adult Offspring
2014 · Matthew V. Cannon, David A. Buchner, et al. · PLoS ONE · 45
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Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver
2014 · Sushabhan Sadhukhan, Yong Han, et al. · Free Radical Biology and Medicine · 13
Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis
2014 · Shenaz Khan, Bassam G. Abu Jawdeh, et al. · Journal of Clinical Investigation · 66
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Lifestyle-Induced Decrease in Fat Mass Improves Adiponectin Secretion in Obese Adults
2014 · KAREN R. KELLY, SANKAR D. NAVANEETHAN, et al. · Medicine & Science in Sports & Exercise · 45
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