Award

Antioxidant enzymes counter reactive oxygen species from steroidogenic cytochrome P450 enzymes in the ovary to limit aneuploidy of embryos

Description: Many birth defects are due to damage sustained by the eggs before ovulation. Aging allows more damage, hence the advice to have babies earlier in life. However, we believe we have identified a source of damage that happens during late development of the follicle in the weeks before ovulation. Proving this will enable us define when an egg is most at risk of damage and to devise strategies to lower the risk.

Funder: National Health and Medical Research Council

Amount: A$537,000

Funding type: research

Funder scheme: Project Grants - Standard Project Grant

Start date: 2018-01-01

End date: 2020-12-31

Investigator: Raymond Rodgers

Institution: University of Adelaide

Topic: Reproductive Biology and Fertility

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

Funded outputs count: 0

Funder award ID: 1143289

OpenAlex ID: G4509852438