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R01 DK120772

Funded outputs count: 10
Funder award ID: R01 DK120772
OpenAlex ID: G4583075532
G Protein‐Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models
2026 · Xun Sun, Connor Mahler, et al. · Obesity
Leptin and G-protein coupled receptor (GPCR) signaling: Therapeutic potential in obesity
2025 · Xun Sun, Lincoln Brueck, et al. · Journal of Biological Chemistry · 3
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Discovery of novel and selective GPR17 antagonists as pharmacological tools for developing new therapeutic strategies in diabetes and obesity
2025 · Hu Zhu, Jason M. Conley, et al. · European Journal of Medicinal Chemistry · 12
Microbiome affects mice metabolic homeostasis via differential regulation of gene expression in the brain and gut
2025 · Wynne Milhouse, Anna Clapp Organski, et al. · Physiological Reports · 5
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G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells
2024 · Jason M. Conley, Alexander Jochim, et al. · Biomolecules · 9
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Dynamic regulation of pancreatic β cell function and gene expression by the SND1 coregulator in vitro
2023 · Sukrati Kanojia, Rebecca K. Davidson, et al. · Islets · 3
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Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion
2022 · Shijun Yan, Jason M. Conley, et al. · Cell Reports · 26
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A high-fat diet catalyzes progression to hyperglycemia in mice with selective impairment of insulin action in Glut4-expressing tissues
2021 · Austin M. Reilly, Shijun Yan, et al. · Journal of Biological Chemistry · 18
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Human GPR17 missense variants identified in metabolic disease patients have distinct downstream signaling profiles
2021 · Jason M. Conley, Hongmao Sun, et al. · Journal of Biological Chemistry · 7
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Metabolic Defects Caused by High-Fat Diet Modify Disease Risk through Inflammatory and Amyloidogenic Pathways in a Mouse Model of Alzheimer’s Disease
2020 · Austin M. Reilly, Andy P. Tsai, et al. · Nutrients · 41
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