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13083

Funded outputs count: 32
Funder award ID: 13083
OpenAlex ID: G4677862955
BRAFV600E-mutated serrated colorectal neoplasia drives transcriptional activation of cholesterol metabolism
2023 · Paulina Rzasa, Sarah Whelan, et al. · Communications Biology · 18
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Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment
2021 · Tamihiro Kamata, Esraa Al Dujaily, et al. · Disease Models & Mechanisms · 9
Digoxin treatment reactivates in vivo radioactive iodide uptake and correlates with favorable clinical outcome in non‐medullary thyroid cancer
2021 · Thomas Crezee, Marika H. Tesselaar, et al. · Cellular Oncology · 13
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Ras/ MAPK dysregulation in development causes a skeletal myopathy in an activating BrafL597V mouse model for cardio‐facio‐cutaneous syndrome
2021 · Yoshiko Maeda, William E. Tidyman, et al. · Developmental Dynamics · 17
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Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development
2020 · Tamihiro Kamata, Tsz Y. So, et al. · Cell Reports · 34
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DNMT3B Oncogenic Activity in Human Intestinal Cancer Is Not Linked to CIMP or BRAFV600E Mutation
2020 · Douglas J. MacKenzie, Neil A. Robertson, et al. · iScience · 10
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Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
2019 · Esraa Al Dujaily, Juvenal Baena, et al. · JNCI Cancer Spectrum · 17
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Early detection of pre-malignant lesions in a KRASG12D-driven mouse lung cancer model by monitoring circulating free DNA
2019 · Callum P. Rakhit, Ricky M. Trigg, et al. · Disease Models & Mechanisms · 21
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Over-expressed, N-terminally truncated BRAF is detected in the nucleus of cells with nuclear phosphorylated MEK and ERK
2018 · Fiona Hey, Catherine Andreadi, et al. · Heliyon · 2
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KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment
2017 · Tamihiro Kamata, Susan Giblett, et al. · Blood · 17
Cyp24a1 Attenuation Limits Progression of BrafV600E -Induced Papillary Thyroid Cancer Cells and Sensitizes Them to BRAFV600E Inhibitor PLX4720
2017 · Minjing Zou, Essa Y. Baitei, et al. · Cancer Research · 20
Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development
2017 · Garyfallia Papaioannou, Elizabeth T. Petit, et al. · Journal of Biological Chemistry · 27
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Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
2016 · Patrizia Cammareri, Aidan M. Rose, et al. · Nature Communications · 111
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Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine
2016 · Fiona Hey, Susan Giblett, et al. · PLoS ONE · 6
Regulation of BRAF protein stability by a negative feedback loop involving the MEK–ERK pathway but not the FBXW7 tumour suppressor
2016 · Maria Aguilar Hernandez, Bipin Patel, et al. · Cellular Signalling · 39
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TSH overcomes BrafV600E-induced senescence to promote tumor progression via downregulation of p53 expression in papillary thyroid cancer
2015 · M Zou, E Y Baitei, et al. · Oncogene · 58
The cholesterol‐binding protein NPC2 restrains recruitment of stromal macrophage‐lineage cells to early‐stage lung tumours
2015 · Tamihiro Kamata, Hong Jin, et al. · EMBO Molecular Medicine · 30
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KRAS-mediated oncogenic transformation of thyroid follicular cells requires long-term TSH stimulation and is regulated by SPRY1
2015 · Minjing Zou, Essa Y Baitei, et al. · Laboratory Investigation · 13
MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients
2015 · Kristiaan Lenos, Jeroen A.C.M. Goos, et al. · Oncotarget · 50
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Characterization of novel markers of senescence and their prognostic potential in cancer
2014 · M Althubiti, L Lezina, et al. · Cell Death and Disease · 256
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Hematopoietic Expression of Oncogenic BRAF Promotes Aberrant Growth of Monocyte-Lineage Cells Resistant to PLX4720
2013 · Tamihiro Kamata, David Dankort, et al. · Molecular Cancer Research · 7
Front Matter
2013 · Gisbert Schneider
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A complex secretory program orchestrated by the inflammasome controls paracrine senescence
2013 · Juan Carlos Acosta, Ana Banito, et al. · Nature Cell Biology · 2,278
A New Mode of RAF Autoregulation: A Further Complication in the Inhibitor Paradox
2013 · Fiona Hey, Catrin Pritchard · Cancer Cell · 9
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Precision medicines for B‐cell leukaemias and lymphomas; progress and potential pitfalls
2013 · Martin J. S. Dyer, Meike Vogler, et al. · British Journal of Haematology · 14
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