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Exploiting the VISTA Pathway to Prevent Acute GVHD and Control Steroid Refractory Disease

Description: Public Health Relevance Our team will gain biological insights into immune system control of graft-versus-host disease (GVHD) providing an exciting new approach for GVHD prevention and therapy. Our findings have broad implications for the use of agonist VISTA antibody for hematopoietic stem cell and solid transplantation as well as autoimmunity settings.

Funder: National Heart, Lung, and Blood Institute

Funding type: research

Funder scheme: R01

Start date: 2021-02-15

End date: 2026-01-31

Investigator: BRUCE R BLAZAR

Institution: UNIVERSITY OF MINNESOTA

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

Funded outputs count: 85

Funder award ID: R01HL155114

OpenAlex ID: G2896368367