Award

Towards Multisystem-Brain Successful Aging in Schizophrenia Spectrum

Description: Contact PD/PI: Hong, L. Elliot Project Narrative Schizophrenia spectrum disorders are associated with high morbidity and mortality rates from common medical conditions that normally increase with age in the general population. How a mental illness conceptualized primarily as brain disorder would have such negative multisystem medical consequence is not explained. This study attempts to identify what are the abnormal brain circuitry and brain-body interaction in the stress response system that may predict the exaggerated brain and body aging and the medical comorbidity in patients with schizophrenia spectrum disorders, so that we can develop better prevention and treatment to promote normal, successful aging. Project Narrative Page 7
Funding type: research
Funder scheme: R01
Start date: 2018-08-01
End date: 2025-04-30
Investigator: L ELLIOT ELLIOT HONG
Institution: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
Funded outputs count: 147
Funder award ID: R01MH116948
OpenAlex ID: G3659509988
2026 · Peter Kochunov, Si Gao, et al. · Molecular Psychiatry · 1
2025 · Caroline Simon Sherman, Erik Gunnarsson, et al. · Bioengineering
2025 · Samantha Narvaez, Krista Wisner, et al. · Journal of Psychiatric Research
2025 · Alia R. Warner, Xiaoming Du, et al. · Journal of Psychiatric Research
2025 · Xinglin Zeng, Yiran Li, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
2025 · A. Ankeeta, Ashutosh Tripathi, et al. · Neuropsychopharmacology · 3
2025 · Hongjie Ke, Bhim M. Adhikari, et al. · Brain Sciences
2025 · A. Ankeeta, Ashutosh Tripathi, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2025 · Samantha Narvaez, Yizhou Ma, et al. · Brain Behavior & Immunity - Health · 1
2025 · Gianpaolo Del Mauro, Yiran Li, et al. · Journal of Pain · 8
2025 · Li Feng, Zhenyao Ye, et al. · EBioMedicine · 11
2025 · Peter Kochunov, Bhim M. Adhikari, et al. · JAMA Psychiatry · 23
2025 · Wolfgang Omlor, Finn Rabe, et al. · American Journal of Psychiatry · 22
2025 · Amanda L. Rodrigue, Emma E. M. Knowles, et al. · Human Brain Mapping · 3
2024 · Alejandro Arbona-Lampaya, Heejong Sung, et al. · Journal of Affective Disorders · 2
Year
Topic