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Systemic rejuvenating factors and human aging phenotypes.

Description: This project is relevant to public health as it aims to characterize the relationship between candidate circulating rejuvenating factors with aging-related phenotypes in humans.
Funding type: research
Funder scheme: R01
Start date: 2018-09-30
End date: 2024-05-31
Investigator: RICHARD D SEMBA
Institution: JOHNS HOPKINS UNIVERSITY
Funded outputs count: 20
Funder award ID: R01AG057723
OpenAlex ID: G1798173940
Relationships of GDF8 and 11 and Their Antagonists With Decline of Grip Strength Among Older Adults in the Baltimore Longitudinal Study of Aging
2023 · Yuko Yamaguchi, Min Zhu, et al. · The Journals of Gerontology Series A · 1
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Plasma Growth and Differentiation Factor 15 Predict Longitudinal Changes in Bone Parameters in Women, but Not in Men
2022 · Yusuke Osawa, Toshiko Tanaka, et al. · The Journals of Gerontology Series A · 7
Proteins in the pathway from high red blood cell width distribution to all-cause mortality
2022 · Yusuke Osawa, Toshiko Tanaka, et al. · EBioMedicine · 28
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The Plasma Proteome Fingerprint Associated with Circulating Carotenoids and Retinol in Older Adults
2021 · Yuko Yamaguchi, Marta Zampino, et al. · Journal of Nutrition · 13
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Proteomics in aging research: A roadmap to clinical, translational research
2021 · Ruin Moaddel, Ceereena Ubaida‐Mohien, et al. · Aging Cell · 139
Plasma metabolites associated with chronic kidney disease and renal function in adults from the Baltimore Longitudinal Study of Aging
2021 · Yuko Yamaguchi, Marta Zampino, et al. · Metabolomics · 68
Elevated Plasma Growth and Differentiation Factor 15 Predicts Incident Anemia in Older Adults Aged 60 Years and Older
2020 · Yuko Yamaguchi, Marta Zampino, et al. · The Journals of Gerontology Series A · 12
A Plasma Proteomic Signature of Skeletal Muscle Mitochondrial Function
2020 · Marta Zampino, Toshiko Tanaka, et al. · International Journal of Molecular Sciences · 15
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Carotenoids and healthy aging: the fascination continues
2020 · Benedetta Bartali, Richard D Semba · American Journal of Clinical Nutrition · 12
Greater Skeletal Muscle Oxidative Capacity Is Associated With Higher Resting Metabolic Rate: Results From the Baltimore Longitudinal Study of Aging
2020 · Marta Zampino, Richard D Semba, et al. · The Journals of Gerontology Series A · 47
Plasma proteomic signature of the risk of developing mobility disability: A 9‐year follow‐up
2020 · Yusuke Osawa, Richard D. Semba, et al. · Aging Cell · 59
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Perspective: The Potential Role of Circulating Lysophosphatidylcholine in Neuroprotection against Alzheimer Disease
2020 · Richard D Semba · Advances in Nutrition · 79
Motoric cognitive risk syndrome: Integration of two early harbingers of dementia in older adults
2020 · Richard D. Semba, Qu Tian, et al. · Ageing Research Reviews · 88
Biomarkers in the path from cellular senescence to frailty
2019 · Marta Zampino, Luigi Ferrucci, et al. · Experimental Gerontology · 36
Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
2019 · Ceereena Ubaida-Mohien, Alexey Lyashkov, et al. · eLife · 232
Aging Skeletal Muscle Proteomics Finds Changes in Spliceosome, Immune factors, Proteostasis and Mitochondria
2019 · Ceereena Ubaida-Mohien, Alexey Lyashkov, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Tetra-linoleoyl cardiolipin depletion plays a major role in the pathogenesis of sarcopenia
2019 · Richard D. Semba, Ruin Moaddel, et al. · Medical Hypotheses · 42
Elevated Plasma Growth and Differentiation Factor 15 Is Associated With Slower Gait Speed and Lower Physical Performance in Healthy Community-Dwelling Adults
2019 · Richard D Semba, Marta Gonzalez-Freire, et al. · The Journals of Gerontology Series A · 94
Low plasma lysophosphatidylcholines are associated with impaired mitochondrial oxidative capacity in adults in the Baltimore Longitudinal Study of Aging
2019 · Richard D. Semba, Pingbo Zhang, et al. · Aging Cell · 73
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Relationship of Circulating Growth and Differentiation Factors 8 and 11 and Their Antagonists as Measured Using Liquid Chromatography–Tandem Mass Spectrometry With Age and Skeletal Muscle Strength in Healthy Adults
2018 · Richard D Semba, Pingbo Zhang, et al. · The Journals of Gerontology Series A · 22
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