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LY18H060012

Funded outputs count: 24
Funder award ID: LY18H060012
OpenAlex ID: G5064365653
Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells
2022 · Chenghao Ren, Jie Jin, et al. · Journal of Cell Science · 38
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Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
2021 · Chenghao Ren, Jie Jin, et al. · Frontiers in Pharmacology · 35
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Cycloastragenol and Astragaloside IV activate telomerase and protect nucleus pulposus cells against high glucose‑induced senescence and apoptosis
2021 · Haofeng Hong, Jian Xiao, et al. · Experimental and Therapeutic Medicine · 47
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High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes
2021 · Ben Wang, Yifeng Shi, et al. · Cell Death and Disease · 40
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Inhibition of LRRK2 restores parkin-mediated mitophagy and attenuates intervertebral disc degeneration
2021 · Jialiang Lin, Xuanqi Zheng, et al. · Osteoarthritis and Cartilage · 45
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STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway
2021 · Qiang Guo, Ximiao Chen, et al. · Cell Death and Disease · 256
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RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration
2020 · Zhenxuan Shao, Libin Ni, et al. · Cell Proliferation · 47
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RNA-Binding Protein HuR Suppresses Inflammation and Promotes Extracellular Matrix Homeostasis via NKRF in Intervertebral Disc Degeneration
2020 · Zhenxuan Shao, Zhuolong Tu, et al. · Frontiers in Cell and Developmental Biology · 17
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Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway
2020 · Jialiang Lin, Jinru Zhuge, et al. · Free Radical Biology and Medicine · 132
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies
2020 · Zhenxuan Shao, Jiajie Lu, et al. · Food & Function · 24
Grape seed procyanidins suppress the apoptosis and senescence of chondrocytes and ameliorates osteoarthritis via the DPP4-Sirt1 pathway
2020 · Ke Wang, Xibang Chen, et al. · Food & Function · 35
Dual regulation of microglia and neurons by Astragaloside IV‐mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury
2019 · Jialiang Lin, Xiangxiang Pan, et al. · Journal of Cellular and Molecular Medicine · 48
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The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics
2019 · Zengjie Zhang, Jialiang Lin, et al. · Oxidative Medicine and Cellular Longevity · 44
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Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration
2019 · Jialiang Lin, Jiaoxiang Chen, et al. · Frontiers in Pharmacology · 50
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BRD4 inhibition regulates MAPK, NF‐κB signals, and autophagy to suppress MMP‐13 expression in diabetic intervertebral disc degeneration
2019 · Jianle Wang, Jianing Hu, et al. · The FASEB Journal · 68
BRD4 inhibition attenuates inflammatory response in microglia and facilitates recovery after spinal cord injury in rats
2019 · Jianle Wang, Jiaoxiang Chen, et al. · Journal of Cellular and Molecular Medicine · 76
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TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux
2018 · Gang Zheng, Zongyou Pan, et al. · Osteoarthritis and Cartilage · 97
Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice
2018 · Haiming Jin, Zengjie Zhang, et al. · Experimental & Molecular Medicine · 94
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Small molecule natural compound agonist of SIRT3 as a therapeutic target for the treatment of intervertebral disc degeneration
2018 · Jianle Wang, Majid Nisar, et al. · Experimental & Molecular Medicine · 98
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Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1‐autophagy pathway
2018 · Zengjie Zhang, Jialiang Lin, et al. · Journal of Cellular and Molecular Medicine · 88
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Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats
2018 · Jianle Wang, Chongan Huang, et al. · Journal of Cellular and Molecular Medicine · 59
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TFEB, a potential therapeutic target for osteoarthritis via autophagy regulation
2018 · Gang Zheng, Yu Zhan, et al. · Cell Death and Disease · 95
Monascin inhibits IL-1β induced catabolism in mouse chondrocytes and ameliorates murine osteoarthritis
2018 · Gang Zheng, Yu Zhan, et al. · Food & Function · 54
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis
2018 · Jianle Wang, Ke Wang, et al. · International Journal of Biological Sciences · 83
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