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NS-056218

Funded outputs count: 47
Funder award ID: NS-056218
OpenAlex ID: G5067898320
Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy
2023 · Stacy A. Hussong, Andy Q. Banh, et al. · Nature Communications · 85
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Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging
2022 · Lauren R. Miller, Stefano Tarantini, et al. · Frontiers in Aging Neuroscience · 28
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Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults
2021 · Tamas Csipo, Agnes Lipecz, et al. · PLoS ONE · 73
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Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain
2020 · Tamas Kiss, Ádám Nyúl-Tóth, et al. · GeroScience · 203
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Fusogenic liposomes effectively deliver resveratrol to the cerebral microcirculation and improve endothelium-dependent neurovascular coupling responses in aged mice
2019 · Tabea Wiedenhoeft, Stefano Tarantini, et al. · GeroScience · 61
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Overexpression of catalase targeted to mitochondria improves neurovascular coupling responses in aged mice
2019 · Anna Csiszar, Andriy Yabluchanskiy, et al. · GeroScience · 69
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Treatment with the poly(ADP-ribose) polymerase inhibitor PJ-34 improves cerebromicrovascular endothelial function, neurovascular coupling responses and cognitive performance in aged mice, supporting the NAD+ depletion hypothesis of neurovascular aging
2019 · Stefano Tarantini, Andriy Yabluchanskiy, et al. · GeroScience · 104
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Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation
2019 · Zoltan Ungvari, Stefano Tarantini, et al. · Frontiers in Genetics · 38
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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
2019 · Stefano Tarantini, Marta Noa Valcarcel-Ares, et al. · Redox Biology · 285
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Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research
2019 · Anna Csiszar, Priya Balasubramanian, et al. · GeroScience · 30
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Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability
2018 · Stefano Tarantini, Andriy Yabluchanskiy, et al. · The Journals of Gerontology Series A · 23
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IGF-1 Deficiency Promotes Pathological Remodeling of Cerebral Arteries: A Potential Mechanism Contributing to the Pathogenesis of Intracerebral Hemorrhages in Aging
2018 · Gabor A Fulop, Francisco I Ramirez-Perez, et al. · The Journals of Gerontology Series A · 56
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Treatment with the mitochondrial‐targeted antioxidant peptide SS ‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
2018 · Stefano Tarantini, Noa M. Valcarcel‐Ares, et al. · Aging Cell · 193
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Pharmacologically induced impairment of neurovascular coupling responses alters gait coordination in mice
2017 · Stefano Tarantini, Andriy Yabluchanksiy, et al. · GeroScience · 57
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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype
2017 · Stefano Tarantini, M Noa Valcarcel-Ares, et al. · The Journals of Gerontology Series A · 164
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Connective tissue growth factor (CTGF) in age-related vascular pathologies
2017 · Zoltan Ungvari, Marta Noa Valcarcel-Ares, et al. · GeroScience · 61
Demonstration of impaired neurovascular coupling responses in TG2576 mouse model of Alzheimer’s disease using functional laser speckle contrast imaging
2017 · Stefano Tarantini, Gabor A. Fulop, et al. · GeroScience · 91
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Insulin-like growth factor 1 deficiency exacerbates hypertension-induced cerebral microhemorrhages in mice, mimicking the aging phenotype
2017 · Stefano Tarantini, Noa M. Valcarcel-Ares, et al. · Aging Cell · 105
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The GH/IGF-1 axis in a critical period early in life determines cellular DNA repair capacity by altering transcriptional regulation of DNA repair-related genes: implications for the developmental origins of cancer
2017 · Andrej Podlutsky, Marta Noa Valcarcel-Ares, et al. · GeroScience · 77
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Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence
2017 · Zoltan Ungvari, Stefano Tarantini, et al. · GeroScience · 101
IGF-1 deficiency in a critical period early in life influences the vascular aging phenotype in mice by altering miRNA-mediated post-transcriptional gene regulation: implications for the developmental origins of health and disease hypothesis
2016 · Stefano Tarantini, Cory B. Giles, et al. · AGE · 41
Pharmacologically-Induced Neurovascular Uncoupling is Associated with Cognitive Impairment in Mice
2015 · Stefano Tarantini, Peter Hertelendy, et al. · Journal of Cerebral Blood Flow & Metabolism · 144
Growth hormone, insulin-like growth factor-1 and the aging brain
2014 · Nicole M. Ashpole, Jessica E. Sanders, et al. · Experimental Gerontology · 226
Systemic influences contribute to prolonged microvascular rarefaction after brain irradiation: a role for endothelial progenitor cells
2014 · Nicole M. Ashpole, Junie P. Warrington, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 27
Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase
2013 · Peter Toth, Stefano Tarantini, et al. · American Journal of Physiology-Heart and Circulatory Physiology · 200
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