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Epitranscriptomics in neurological disease

Description: Epilepsy is a disease caused by uncontrolled firing of brain cells, leading to seizures. Some DNA mutations have been discovered that make people more susceptible to epilepsy, however in most cases no clear mutations are responsible for the disease. Epilepsy may be partly caused by changes in the sequence of RNA molecules (copies of DNA), some of which are required for correct brain function. This project will develop and apply computing tools to understand epilepsy-associated RNA changes.
Amount: A$327,200
Funding type: fellowship
Funder scheme: Early Career Fellowships - Peter Doherty Biomedical ECF
Investigator: Brendan Ansell
Institution: Walter and Eliza Hall Institute of Medical Research
Funded outputs count: 16
Funder award ID: 1157776
OpenAlex ID: G5177677761
2024 · Samaneh Farashi, Roberto Bonelli, et al. · Ophthalmology Science · 2
2023 · B RE Ansell, R Bonelli, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
2023 · Kevin T. Eade, Brendan Robert E. Ansell, et al. · Journal of Clinical Investigation · 12
2023 · Courtney R. Green, Roberto Bonelli, et al. · Molecular Metabolism · 19
2022 · Roberto Bonelli, Brendan R E Ansell, et al. · bioRxiv (Cold Spring Harbor Laboratory)
2022 · Mathieu Barbier, Melanie Bahlo, et al. · Annals of Neurology · 26
2022 · Samaneh Farashi, Brendan R.E. Ansell, et al. · Trends in Genetics · 7
2021 · Brendan Robert E. Ansell, Simon N. Thomas, et al. · RNA · 18
2021 · Roberto Bonelli, Victoria E. Jackson, et al. · Communications Biology · 36
2020 · Roberto Bonelli, Sasha M. Woods, et al. · Scientific Reports · 36
2020 · Samantha J Emery-Corbin, Joshua J Hamey, et al. · Molecular Biology and Evolution · 14
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