Cysteine oxidation in the heart
Description: Lay summary Heart cells cannot contract strongly in heart failure patients. We will investigate how a molecule important for maintaining a strong heartbeat is damaged by harmful mechanisms and destroyed in the heart during stress Understanding the step-by-step mechanisms by which this key protein in the heart is destroyed during heart failure should provide valuable information for developing a novel intervention to treat heart failure.
Funding type: research
Funder scheme: R01
Start date: 2008-01-15
End date: 2028-04-30
Investigator: JUNICHI SADOSHIMA
Institution: RUTGERS BIOMEDICAL AND HEALTH SCIENCES
Funded outputs count: 185
Funder award ID: R01HL091469
OpenAlex ID: G9000871788