Early life influences on Epigenetic Aging in Mexican-American children
Description: Project Narrative Age acceleration, the difference between one’s biological age determined by their epigenetic clock, and one’s chronological age has been associated with age-related conditions like pubertal development, obesity, and cancer. In this proposal, we will use state of the art methodologies to estimate epigenetic clocks in Mexican- American children participating in the CHAMACOS study and identify early life factors during pregnancy and at birth (gestational age and birthweight) that may affect epigenetic age acceleration during childhood. Understanding the factors that impact age acceleration will help us elucidate the biological and developmental processes that influence age-related phenotypes.
Funder: National Institute on Aging
Funding type: research
Funder scheme: R03
Start date: 2020-05-01
End date: 2023-01-31
Investigator: NINA T HOLLAND
Institution: UNIVERSITY OF CALIFORNIA BERKELEY
Field: Medicine
Domain: Health Sciences
Funded outputs count: 23
Funder award ID: R03AG067064
OpenAlex ID: G3971821495